O2 variant chip to simulate site-specific skeletogenesis from hypoxic bone marrow

The stemness of bone marrow mesenchymal stem cells (BMSCs) is maintained by hypoxia. The oxygen level increases from vessel-free cartilage to hypoxic bone marrow and, furthermore, to vascularized bone, which might direct the chondrogenesis to osteogenesis and regenerate the skeletal system. Hence, o...

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Veröffentlicht in:	Science advances 2023-03, Vol.9 (12), p.eadd4210-eadd4210
Hauptverfasser:	Kim, Hye-Seon, Ha, Hyun-Su, Kim, Dae-Hyun, Son, Deok Hyeon, Baek, Sewoom, Park, Jeongeun, Lee, Chan Hee, Park, Suji, Yoon, Hyo-Jin, Yu, Seung Eun, Kang, Jeon Il, Park, Kyung Min, Shin, Young Min, Lee, Jung Bok, Sung, Hak-Joon
Format:	Artikel
Sprache:	eng
Schlagworte:	Applied Sciences and Engineering Biomedicine and Life Sciences Engineering SciAdv r-articles
Online-Zugang:	Volltext
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