Nephronectin is required to maintain right lung lobar separation during embryonic development

Nephronectin (NPNT) is a basement membrane (BM) protein and high-affinity ligand of integrin α8β1 that is required for kidney morphogenesis in mice. In the lung, NPNT also localizes to BMs, but its potential role in pulmonary development has not been investigated. Mice with a floxed allele were used...

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Veröffentlicht in:	American journal of physiology. Lung cellular and molecular physiology 2023-03, Vol.324 (3), p.L335-L344
Hauptverfasser:	Wilson, Carole L, Hung, Chi F, Burkel, Brian M, Ponik, Suzanne M, Gharib, Sina A, Schnapp, Lynn M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Collagen Embryonic Development - genetics Extracellular Matrix Proteins - genetics Lung - metabolism Membrane Proteins Mice
Online-Zugang:	Volltext
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