Insights on the interaction of SARS-CoV-2 variant B.1.617.2 with antibody CR3022 and analysis of antibody resistance

Background The existence of mutated Delta (B.1.617.2) variants of SARS-CoV-2 causes rapid transmissibility, increase in virulence, and decrease in the effectiveness of public health. Majority of mutations are seen in the surface spike, and they are considered as antigenicity and immunogenicity of th...

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Veröffentlicht in:	Journal of Genetic Engineering and Biotechnology 2023-12, Vol.21 (1), p.35-15, Article 35
Hauptverfasser:	KS, Sandhya, Nair, Achuthsankar S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Affinity Amino acids Analysis Antibodies Antigenicity Binding Bioinformatics Biomedical Engineering and Bioengineering Biotechnology Coronaviruses COVID-19 vaccines CR3022 Delta Disease transmission Engineering Entropy Free energy Genetic Engineering Genetics and Genomics Glycoproteins Health aspects Homology modelling Hydrogen Hydrogen bonds Immunogenicity Molecular docking Molecular dynamics Monoclonal antibodies Mutation Proteins Proteomics Public health SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 Spike protein Temperature dependence Vaccines Viral diseases Virulence
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