HER3 PET Imaging Predicts Response to Pan Receptor Tyrosine Kinase Inhibition Therapy in Gastric Cancer

Purpose New generation of receptor tyrosine kinase inhibitors (RTKIs) have shown to improve survival in many solid tumors. However, an imaging biomarker is needed for patient selection and prediction of treatment response. This study evaluates the use of quantitative changes of HER3 on 68 Ga-NOTA-H...

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Veröffentlicht in:	Molecular imaging and biology 2023-04, Vol.25 (2), p.353-362
Hauptverfasser:	Esfahani, Shadi A., de Aguiar Ferreira, Carolina, Rotile, Nicholas J., Ataeinia, Bahar, Krishna, Shriya, Catalano, Onofrio A., Caravan, Peter, Yen, Yi-Fen, Heidari, Pedram, Mahmood, Umar
Format:	Artikel
Sprache:	eng
Schlagworte:	Afatinib - pharmacology AKT protein Biomarkers Cancer Cell Line, Tumor Cell viability Evaluation Gastric cancer Growth rate Humans Imaging Kinases Magnetic resonance imaging MAP kinase Medical imaging Medicine Medicine & Public Health Nodes Positron emission Positron-Emission Tomography - methods Protein-tyrosine kinase receptors Radiology Receptor, ErbB-3 Receptors Research Article Solid tumors Stomach Neoplasms - pathology Tumor cell lines Tumors Tyrosine Xenografts Xenotransplantation
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