Chemical Wastes in the Peptide Synthesis Process and Ways to Reduce Them

In recent decades, a growing interest has been observed among pharmaceutical companies in producing and selling 80 FDA-approved therapeutic peptides. However, there are many drawbacks to peptide synthesis at the academic and industrial scales, involving the use of large amounts of highly hazardous c...

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Veröffentlicht in:	Iranian journal of pharmaceutical research : IJPR 2022-12, Vol.21 (1), p.e123879
Hauptverfasser:	Haji Abbasi Somehsaraie, Mahan, Fathi Vavsari, Vaezeh, Kamangar, Mohammad, Balalaie, Saeed
Format:	Artikel
Sprache:	eng
Schlagworte:	Review
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creator	Haji Abbasi Somehsaraie, Mahan Fathi Vavsari, Vaezeh Kamangar, Mohammad Balalaie, Saeed
description	In recent decades, a growing interest has been observed among pharmaceutical companies in producing and selling 80 FDA-approved therapeutic peptides. However, there are many drawbacks to peptide synthesis at the academic and industrial scales, involving the use of large amounts of highly hazardous coupling reagents and solvents. This review focuses on hideous and observant wastes produced before, during, and after peptide synthesis and proposes some solutions to reduce them.
doi_str_mv	10.5812/ijpr-123879
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title	Chemical Wastes in the Peptide Synthesis Process and Ways to Reduce Them
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