Systemic Hypoxemia Induces Cardiomyocyte Hypertrophy and Right Ventricular Specific Induction of Proliferation

A recent study suggests that systemic hypoxemia in adult male mice can induce cardiac myocytes to proliferate. The goal of the present experiments was to confirm these results, provide new insights on the mechanisms that induce adult cardiomyocyte cell cycle reentry, and to determine if hypoxemia al...

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Veröffentlicht in:	Circulation research 2023-03, Vol.132 (6), p.723-740
Hauptverfasser:	Johnson, Jaslyn, Yang, Yijun, Bian, Zilin, Schena, Giana, Li, Yijia, Zhang, Xiaoying, Eaton, Deborah M., Gross, Polina, Angheloiu, Alexandra, Shaik, Arshadullah, Foster, Michael, Berretta, Remus, Kubo, Hajime, Mohsin, Sadia, Tian, Ying, Houser, Steven R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Proliferation Female Hypertrophy - complications Hypertrophy - metabolism Hypoxia - complications Hypoxia - metabolism Male Mice Mice, Inbred C57BL Myocytes, Cardiac - metabolism Oxygen - metabolism
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