Bilateral Adrenal Myelolipomas in a Female Patient With Undiagnosed Non-classic Congenital Adrenal Hyperplasia
Non-classic congenital adrenal hyperplasia (CAH) usually presents later in life with signs of androgen excess but may also be diagnosed after the detection of an incidental adrenal myelolipoma. This is a patient with previously undiagnosed CAH who presented to the emergency department with chest dis...
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| Veröffentlicht in: | Curēus (Palo Alto, CA) CA), 2023-02, Vol.15 (2), p.e35017 |
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| creator | Vemula, Bhavana R Olajide, Omolola B Adepoju, Yewande |
| description | Non-classic congenital adrenal hyperplasia (CAH) usually presents later in life with signs of androgen excess but may also be diagnosed after the detection of an incidental adrenal myelolipoma. This is a patient with previously undiagnosed CAH who presented to the emergency department with chest discomfort and palpitations. A computed tomography (CT) scan of the chest done to rule out pulmonary embolism showed bilateral large adrenal myelolipomas. She also had evidence of marked hirsutism on examination, which prompted further workup, and her laboratory data was in keeping with CAH. Further management was unable to be pursued due to the patient's poor compliance, and she was subsequently lost to follow-up. Chronic exposure of the adrenal glands to high adrenocorticotropic hormone (ACTH) levels increases the risk of developing myelolipomas. CAH needs to be considered as a diagnosis in the evaluation of incidental adrenal myelolipomas. |
| doi_str_mv | 10.7759/cureus.35017 |
| format | Article |
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This is a patient with previously undiagnosed CAH who presented to the emergency department with chest discomfort and palpitations. A computed tomography (CT) scan of the chest done to rule out pulmonary embolism showed bilateral large adrenal myelolipomas. She also had evidence of marked hirsutism on examination, which prompted further workup, and her laboratory data was in keeping with CAH. Further management was unable to be pursued due to the patient's poor compliance, and she was subsequently lost to follow-up. Chronic exposure of the adrenal glands to high adrenocorticotropic hormone (ACTH) levels increases the risk of developing myelolipomas. CAH needs to be considered as a diagnosis in the evaluation of incidental adrenal myelolipomas.</description><identifier>ISSN: 2168-8184</identifier><identifier>EISSN: 2168-8184</identifier><identifier>DOI: 10.7759/cureus.35017</identifier><identifier>PMID: 36938181</identifier><language>eng</language><publisher>United States: Cureus Inc</publisher><subject>Abdomen ; Asymptomatic ; Congenital diseases ; Diabetes ; Dopamine ; Endocrinology ; Endocrinology/Diabetes/Metabolism ; Enzymes ; Hormones ; Hyperplasia ; Insulin-like growth factors ; Laboratories ; Metabolism ; Nursing ; Patients ; Plasma ; Steroids ; Tomography ; Tumors ; Urine</subject><ispartof>Curēus (Palo Alto, CA), 2023-02, Vol.15 (2), p.e35017</ispartof><rights>Copyright © 2023, Vemula et al.</rights><rights>Copyright © 2023, Vemula et al. This work is published under https://creativecommons.org/licenses/by/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright © 2023, Vemula et al. 2023 Vemula et al.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c310t-a0d3ecd1cd17b728a45e33c1049adb5eff19ff6ed844609e11481bfa759af0ef3</citedby><cites>FETCH-LOGICAL-c310t-a0d3ecd1cd17b728a45e33c1049adb5eff19ff6ed844609e11481bfa759af0ef3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022842/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022842/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27923,27924,53790,53792</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36938181$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Vemula, Bhavana R</creatorcontrib><creatorcontrib>Olajide, Omolola B</creatorcontrib><creatorcontrib>Adepoju, Yewande</creatorcontrib><title>Bilateral Adrenal Myelolipomas in a Female Patient With Undiagnosed Non-classic Congenital Adrenal Hyperplasia</title><title>Curēus (Palo Alto, CA)</title><addtitle>Cureus</addtitle><description>Non-classic congenital adrenal hyperplasia (CAH) usually presents later in life with signs of androgen excess but may also be diagnosed after the detection of an incidental adrenal myelolipoma. This is a patient with previously undiagnosed CAH who presented to the emergency department with chest discomfort and palpitations. A computed tomography (CT) scan of the chest done to rule out pulmonary embolism showed bilateral large adrenal myelolipomas. She also had evidence of marked hirsutism on examination, which prompted further workup, and her laboratory data was in keeping with CAH. Further management was unable to be pursued due to the patient's poor compliance, and she was subsequently lost to follow-up. Chronic exposure of the adrenal glands to high adrenocorticotropic hormone (ACTH) levels increases the risk of developing myelolipomas. CAH needs to be considered as a diagnosis in the evaluation of incidental adrenal myelolipomas.</description><subject>Abdomen</subject><subject>Asymptomatic</subject><subject>Congenital diseases</subject><subject>Diabetes</subject><subject>Dopamine</subject><subject>Endocrinology</subject><subject>Endocrinology/Diabetes/Metabolism</subject><subject>Enzymes</subject><subject>Hormones</subject><subject>Hyperplasia</subject><subject>Insulin-like growth factors</subject><subject>Laboratories</subject><subject>Metabolism</subject><subject>Nursing</subject><subject>Patients</subject><subject>Plasma</subject><subject>Steroids</subject><subject>Tomography</subject><subject>Tumors</subject><subject>Urine</subject><issn>2168-8184</issn><issn>2168-8184</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNpVUU1LxDAQDaKoqDfPEvBq10zT7cdJdPEL1o-D4jHMtpM10k1q0gr7742uygoDM_Aeb97MY-wQxKgoxtVpPXgawkiOBRQbbDeFvExKKLPNtXmHHYTwJoQAUaSiENtsR-aVjBDsMnthWuzJY8vPG0829rslta41nVtg4MZy5Fe0wJb4I_aGbM9fTP_Kn21jcG5doIbfO5vULYZgaj5xdk7W9GuCN8uOfBdxg_tsS2Mb6OCn77Hnq8unyU0yfbi-nZxPk1qC6BMUjaS6gVjFrEhLzMYkZQ0iq7CZjUlrqLTOqSmzLBcVAWQlzDTGl6AWpOUeO1vpdsNsQU0dbccTVefNAv1SOTTqP2LNq5q7DwVCpGmZpVHh-EfBu_eBQq_e3ODjOUGlRSUl5FDlkXWyYtXeheBJ_60Aob4SUquE1HdCkX60buuP_JuH_ARRg5AG</recordid><startdate>20230215</startdate><enddate>20230215</enddate><creator>Vemula, Bhavana R</creator><creator>Olajide, Omolola B</creator><creator>Adepoju, Yewande</creator><general>Cureus Inc</general><general>Cureus</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>5PM</scope></search><sort><creationdate>20230215</creationdate><title>Bilateral Adrenal Myelolipomas in a Female Patient With Undiagnosed Non-classic Congenital Adrenal Hyperplasia</title><author>Vemula, Bhavana R ; 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This is a patient with previously undiagnosed CAH who presented to the emergency department with chest discomfort and palpitations. A computed tomography (CT) scan of the chest done to rule out pulmonary embolism showed bilateral large adrenal myelolipomas. She also had evidence of marked hirsutism on examination, which prompted further workup, and her laboratory data was in keeping with CAH. Further management was unable to be pursued due to the patient's poor compliance, and she was subsequently lost to follow-up. Chronic exposure of the adrenal glands to high adrenocorticotropic hormone (ACTH) levels increases the risk of developing myelolipomas. CAH needs to be considered as a diagnosis in the evaluation of incidental adrenal myelolipomas.</abstract><cop>United States</cop><pub>Cureus Inc</pub><pmid>36938181</pmid><doi>10.7759/cureus.35017</doi><oa>free_for_read</oa></addata></record> |
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| subjects | Abdomen Asymptomatic Congenital diseases Diabetes Dopamine Endocrinology Endocrinology/Diabetes/Metabolism Enzymes Hormones Hyperplasia Insulin-like growth factors Laboratories Metabolism Nursing Patients Plasma Steroids Tomography Tumors Urine |
| title | Bilateral Adrenal Myelolipomas in a Female Patient With Undiagnosed Non-classic Congenital Adrenal Hyperplasia |
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