Upregulation of GALNT7 in prostate cancer modifies O-glycosylation and promotes tumour growth

Prostate cancer is the most common cancer in men and it is estimated that over 350,000 men worldwide die of prostate cancer every year. There remains an unmet clinical need to improve how clinically significant prostate cancer is diagnosed and develop new treatments for advanced disease. Aberrant gl...

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Veröffentlicht in:	Oncogene 2023-03, Vol.42 (12), p.926-937
Hauptverfasser:	Scott, Emma, Hodgson, Kirsty, Calle, Beatriz, Turner, Helen, Cheung, Kathleen, Bermudez, Abel, Marques, Fernando Jose Garcia, Pye, Hayley, Yo, Edward Christopher, Islam, Khirul, Oo, Htoo Zarni, McClurg, Urszula L., Wilson, Laura, Thomas, Huw, Frame, Fiona M., Orozco-Moreno, Margarita, Bastian, Kayla, Arredondo, Hector M., Roustan, Chloe, Gray, Melissa Anne, Kelly, Lois, Tolson, Aaron, Mellor, Ellie, Hysenaj, Gerald, Goode, Emily Archer, Garnham, Rebecca, Duxfield, Adam, Heavey, Susan, Stopka-Farooqui, Urszula, Haider, Aiman, Freeman, Alex, Singh, Saurabh, Johnston, Edward W., Punwani, Shonit, Knight, Bridget, McCullagh, Paul, McGrath, John, Crundwell, Malcolm, Harries, Lorna, Bogdan, Denisa, Westaby, Daniel, Fowler, Gemma, Flohr, Penny, Yuan, Wei, Sharp, Adam, de Bono, Johann, Maitland, Norman J., Wisnovsky, Simon, Bertozzi, Carolyn R., Heer, Rakesh, Guerrero, Ramon Hurtado, Daugaard, Mads, Leivo, Janne, Whitaker, Hayley, Pitteri, Sharon, Wang, Ning, Elliott, David J., Schumann, Benjamin, Munkley, Jennifer
Format:	Artikel
Sprache:	eng
Schlagworte:	101/58 13/105 631/67/589/466 631/80/221 631/80/83 692/53/2421 82/51 Apoptosis Cell Biology Cell cycle Glycosylation Glycosyltransferase Human Genetics Humans Internal Medicine Male Medicine Medicine & Public Health Metastases Oncology Prostate cancer Prostatic Neoplasms - metabolism Signal Transduction Transcriptional Activation Tumors Up-Regulation
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