Synergistic Effect of SOS Response and GATC Methylome Suppression on Antibiotic Stress Survival in Escherichia coli

The suppression of the SOS response has been shown to enhance the activity of quinolones. Furthermore, Dam-dependent base methylation has an impact on susceptibility to other antimicrobials affecting DNA synthesis. Here, we investigated the interplay between these two processes, alone and in combina...

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Veröffentlicht in:	Antimicrobial agents and chemotherapy 2023-03, Vol.67 (3), p.e0139222-e0139222
Hauptverfasser:	Diaz-Diaz, S, Recacha, E, Pulido, Marina R, Romero-Muñoz, María, de Gregorio-Iaria, B, Docobo-Pérez, F, Pascual, A, Rodríguez-Martínez, J M
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology Antimicrobial Chemotherapy Epigenome Escherichia coli Escherichia coli Proteins - genetics Mutation - genetics Quinolones - pharmacology SOS Response, Genetics Susceptibility
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