Advances in Liver Transplantation: where are we in the pursuit of transplantation tolerance?

Liver transplantation is the ultimate treatment option for end‐stage liver disease. Breakthroughs in surgical practice and immunosuppression have seen considerable advancements in survival after transplantation. However, the intricate management of immunosuppressive regimens, balancing desired immun...

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Veröffentlicht in:	European journal of immunology 2021-10, Vol.51 (10), p.2373-2386
Hauptverfasser:	Safinia, Niloufar, Vaikunthanathan, Trishan, Lechler, Robert Ian, Sanchez‐Fueyo, Alberto, Lombardi, Giovanna
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Communication - immunology Cell survival Cell therapy Chimeric antigen receptors Clinical Studies as Topic Clinical trials Clinical Trials as Topic Combined Modality Therapy Hepatocytes Highlights Humans Immunological tolerance Immunomodulation Immunoregulation Immunosuppression immunosuppression withdrawal Immunosuppressive agents Immunotherapy Liver Liver - immunology Liver - metabolism Liver diseases Liver Diseases - etiology Liver Diseases - therapy Liver transplantation Liver Transplantation - adverse effects Liver Transplantation - methods Liver Transplantation - trends Liver transplants Lymphocytes T Models, Animal Morbidity Organ Specificity - immunology regulatory T cells Review\|Basic T-Lymphocyte Subsets - immunology T-Lymphocyte Subsets - metabolism T-Lymphocytes, Regulatory - immunology T-Lymphocytes, Regulatory - metabolism tolerance Toxicity Transplantation Immunology Transplantation Tolerance - immunology
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