The genetic profile and molecular subtypes of human pseudomyxoma peritonei and appendiceal mucinous neoplasms: a systematic review

Pseudomyxoma peritonei (PMP) is a rare, progressive, slowly growing neoplastic condition which is poorly understood, with a 5-year progression-free survival rate as low as 48%. PMP is most commonly caused by appendiceal mucinous neoplasms (AMN), and understanding their genetic biology and pathogenic...

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Veröffentlicht in:	Cancer and metastasis reviews 2023-03, Vol.42 (1), p.335-359
Hauptverfasser:	Murage, Nora Wangari, Ahmed, Nada Mabrouk, Underwood, Timothy J., Walters, Zoë S., Breininger, Stella Panagio
Format:	Artikel
Sprache:	eng
Schlagworte:	Appendiceal Neoplasms - genetics Appendiceal Neoplasms - pathology Appendix Biomedical and Life Sciences Biomedicine Cancer Cancer Research Clinical trials Gastric cancer Gene expression Gene mutations Genetic Profile Humans K-Ras protein Mutation Non-Thematic Review Oncology Oncology, Experimental p53 Protein Pathogenicity Peritoneal Neoplasms - genetics Prognosis Proto-Oncogene Proteins p21(ras) - genetics Pseudomyxoma Peritonei - genetics Pseudomyxoma Peritonei - pathology Survival Systematic review Tumor proteins Tumors
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