Intralesional Infiltrations of Cell-Free Filtrates Derived from Human Diabetic Tissues Delay the Healing Process and Recreate Diabetes Histopathological Changes in Healthy Rats

Lower limb ulcers in type-2 diabetic patients are a frequent complication that tributes to amputation and reduces survival. We hypothesized that diabetic healing impairment and other histopathologic hallmarks are mediated by a T2DM-induced tissue priming/metabolic memory that can be transferred from...

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Veröffentlicht in:Frontiers in clinical diabetes and healthcare (online) 2021-03, Vol.2, p.617741-617741
Hauptverfasser: Berlanga-Acosta, Jorge, Fernández-Mayola, Maday, Mendoza-Marí, Yssel, García-Ojalvo, Ariana, Playford, Raymond J, Guillen-Nieto, Gerardo
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Sprache:eng
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