COVID-19-induced transaminitis and hyperbilirubinemia: Presentation and outcomes

The risk of liver injury in patients with coronavirus disease 2019 (COVID-19) infection is quite evident. Furthermore, liver function test abnormalities are still detected in COVID-19 patients despite the development of antivirals and the availability of several types of vaccines. This editorial des...

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Veröffentlicht in:World journal of gastroenterology : WJG 2023-02, Vol.29 (7), p.1123-1130
Hauptverfasser: Said, Zeinab Nabil Ahmed, El Habashy, Safinaz Adel, Zaky, Samy
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container_issue 7
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container_title World journal of gastroenterology : WJG
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creator Said, Zeinab Nabil Ahmed
El Habashy, Safinaz Adel
Zaky, Samy
description The risk of liver injury in patients with coronavirus disease 2019 (COVID-19) infection is quite evident. Furthermore, liver function test abnormalities are still detected in COVID-19 patients despite the development of antivirals and the availability of several types of vaccines. This editorial describes liver involvement during COVID-19 infection in patients with or without preexisting liver injury, such as chronic liver disease, to elucidate COVID-19-induced liver function abnormalities and their severity, pathophysiology, clinical manifestations, and clinical and laboratory outcomes. We also discuss the effect of vaccination against COVID-19 to better understand host factors, such as age, gender, and race, on the incidence and severity of liver dysfunction at initial presentation and during the illness. Finally, we summarize the results of relevant meta-analyses published to date and highlight the importance of adequate liver function monitoring in the current climate of the overwhelming COVID-19 pandemic.
doi_str_mv 10.3748/wjg.v29.i7.1123
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subjects COVID-19 - complications
Humans
Hyperbilirubinemia - etiology
Liver Diseases - diagnosis
Liver Diseases - epidemiology
Liver Diseases - etiology
Pandemics
SARS-CoV-2
title COVID-19-induced transaminitis and hyperbilirubinemia: Presentation and outcomes
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