Protective Effects of Glycine soja Leaf and Stem Extract against Chondrocyte Inflammation and Osteoarthritis

Wild soybean, also known as Sieb. et Zucc. (GS), has long been known for its various health benefits. Although various pharmacological effects of have been studied, the effects of GS leaf and stem (GSLS) on osteoarthritis (OA) have not been evaluated. Here, we examined the anti-inflammatory effects...

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Veröffentlicht in:	International journal of molecular sciences 2023-03, Vol.24 (5), p.4829
Hauptverfasser:	Lee, Yun Mi, Son, Eunjung, Kim, Seung-Hyung, Kim, Dong-Seon
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arthritis Cartilage Cartilage diseases Chondrocytes Chondrocytes - drug effects Chondrocytes - metabolism Collagen (type II) Cytokines Cytokines - metabolism Degeneration Drug dosages Enzymes Extracellular matrix Flavonoids Glycine Glycine max - chemistry Glycine soja Humans IL-1β In vivo methods and tests Inflammation Inflammation - metabolism Interleukin-1beta - metabolism Joint diseases Leaves Matrix metalloproteinase Matrix metalloproteinases Matrix Metalloproteinases - metabolism Natural products NF-kappa B - metabolism NF-κB protein Osteoarthritis Osteoarthritis - therapy Pain Pain - drug therapy Plant Extracts - pharmacology Plant Extracts - therapeutic use Plant Leaves - chemistry Plant Stems - chemistry Rats Serum levels Soybeans Tumor necrosis factor-TNF
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