Soluble Guanylate Cyclase β1 Subunit Represses Human Glioblastoma Growth

Malignant glioma is the most common and deadly brain tumor. A marked reduction in the levels of sGC (soluble guanylyl cyclase) transcript in the human glioma specimens has been revealed in our previous studies. In the present study, restoring the expression of sGCβ1 alone repressed the aggressive co...

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Veröffentlicht in:	Cancers 2023-03, Vol.15 (5), p.1567
Hauptverfasser:	Xiao, Haijie, Zhu, Haifeng, Bögler, Oliver, Mónica, Fabiola Zakia, Kots, Alexander Y, Murad, Ferid, Bian, Ka
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antitumor activity Brain cancer Brain tumors Cell culture Cell cycle Cyclin-dependent kinase 6 Enzymatic activity Enzymes Glioblastoma Glioblastoma cells Glioblastoma multiforme Glioma cells Guanylate cyclase p53 Protein Proteins Software Xenografts
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