Effect of roxatidine bismuth citrate (MX1) against acetylsalicylic acid- and indomethacin-induced gastric mucosal damage in rats

We have studied the effect of the newly synthesized agent, roxatidine bismuth citrate (N-[3-(3-(1-piperidinyl-methyl)phenoxy)propyl]-hydroxyacetamide-2- hydroxypropane-1,2,3-tricarboxylate-bismuth(3+) complex), code name MX1, against acetylsalicylic acid (ASA)- and indomethacin-induced gastric mucos...

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Veröffentlicht in:	Methods and findings in experimental and clinical pharmacology 1998-10, Vol.20 (8), p.667-672
Hauptverfasser:	MARAZOVA, K, KLOUCHEK, E, POPOV, A, IVANOV, C, KRUSHKOV, I, ICHIKAWA, T, ISHIHARA, K, HOTTA, K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents, Non-Steroidal Anti-Ulcer Agents - therapeutic use Aspirin Biological and medical sciences Digestive system Drug Combinations Drug Evaluation, Preclinical Gastric Mucosa - drug effects Gastric Mucosa - pathology Indomethacin Male Medical sciences Organometallic Compounds - therapeutic use Pharmacology. Drug treatments Piperidines - therapeutic use Rats Rats, Wistar Stomach Ulcer - chemically induced Stomach Ulcer - drug therapy
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