Evaluation of irinotecan in combination with 5-fluorouracil or etoposide in xenograft models of colon adenocarcinoma and rhabdomyosarcoma

Irinotecan [7-ethyl-10-(4-[1-piperidino]-1-piperidino)-carbonyloxy-camptothec in] administered i.v. in two courses, each course consisting of administration every day for 5 days [(dx5)2] on days 1-5 and 8-12, has demonstrated significant activity against advanced human tumor xenografts derived from...

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Veröffentlicht in:	Clinical cancer research 1996-01, Vol.2 (1), p.107-118
Hauptverfasser:	J A Houghton, P J Cheshire, J D Hallman, 2nd, L Lutz, X Luo, Y Li, P J Houghton
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - drug therapy Animals Antineoplastic agents Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Camptothecin - administration & dosage Camptothecin - analogs & derivatives Camptothecin - toxicity Chemotherapy Colonic Neoplasms - drug therapy Etoposide - administration & dosage Female Fluorouracil - administration & dosage Humans Medical sciences Mice Mice, Inbred CBA Neoplasm Transplantation Pharmacology. Drug treatments Rhabdomyosarcoma - drug therapy Transplantation, Heterologous
Online-Zugang:	Volltext
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