Phase II study of all-trans-retinoic acid and alpha-interferon in patients with advanced non-small cell lung cancer

Between April 1993 and June 1994, 29 patients (pts) with unresectable, locally advanced, or metastatic non-small cell lung cancer were treated with a combination of p.o. trans-retinoic acid (TRA), 150 mg/m2/day, in three divided doses and s.c. IFN-alpha, 3 x 10(6) units/day. The age range was 41-80...

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Veröffentlicht in:	Clinical cancer research 1995-09, Vol.1 (9), p.973-979
Hauptverfasser:	ATHANASIADIS, I, KIES, M. S, MILLER, M, GANZENKO, N, JOOB, A, MARYMONT, M.-.A, RADEMAKER, A, GRADISHAR, W. J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - drug therapy Adult Aged Aged, 80 and over Antineoplastic agents Antineoplastic Combined Chemotherapy Protocols - adverse effects Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Carcinoma, Large Cell - drug therapy Carcinoma, Non-Small-Cell Lung - diagnostic imaging Carcinoma, Non-Small-Cell Lung - drug therapy Carcinoma, Non-Small-Cell Lung - pathology Carcinoma, Squamous Cell - drug therapy Combined treatments (chemotherapy of immunotherapy associated with an other treatment) Female Humans Interferon-alpha - administration & dosage Interferon-alpha - adverse effects Lung Neoplasms - diagnostic imaging Lung Neoplasms - drug therapy Lung Neoplasms - pathology Male Medical sciences Middle Aged Neoplasm Staging Pharmacology. Drug treatments Radiography Tretinoin - administration & dosage Tretinoin - adverse effects
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