Microsatellite alterations at 5q21, 11p13, and 11p15.5 do not predict survival in non-small cell lung cancer

We investigated the clinical implications of allelic deletions at three common sites of loss of heterozygosity (LOH) in regions 5q21, 11p15.5, and 11p13 in 86 patients with non-small cell lung cancer (NSCLC). We performed a PCR-based microsatellite polymorphism assay for detection of LOH. The micros...

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Veröffentlicht in:	Clinical cancer research 1997-07, Vol.3 (7), p.1229-1235
Hauptverfasser:	M Sánchez-Céspedes, R Rosell, A Pifarré, M P López-Cabrerizo, A Barnadas, J J Sánchez, J C Lorenzo, A Abad, M Monzó, J J Navas-Palacios
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biological and medical sciences Carcinoma, Non-Small-Cell Lung - genetics Carcinoma, Non-Small-Cell Lung - mortality Carcinoma, Non-Small-Cell Lung - pathology Carcinoma, Non-Small-Cell Lung - surgery Chromosome Mapping Chromosomes, Human, Pair 11 Chromosomes, Human, Pair 5 Female Genetic Markers Humans Loss of Heterozygosity Lung Neoplasms - genetics Lung Neoplasms - mortality Lung Neoplasms - pathology Lung Neoplasms - surgery Lymphatic Metastasis Male Medical sciences Microsatellite Repeats Middle Aged Neoplasm Staging Pneumology Polymerase Chain Reaction Predictive Value of Tests Prognosis Survival Analysis Time Factors Tumors of the respiratory system and mediastinum
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