Relation of glutathione S-transferase alpha and mu isoforms to response to therapy in human breast cancer

Glutathione S-transferase (GST) represents a multifunctional enzyme family consisting of four known cytosolic isoforms (alpha, mu, pi, and Phi) that detoxify a variety of xenobiotic chemicals and may confer resistance to both chemotherapeutic drugs and carcinogens in various experimental models. GST...

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Veröffentlicht in:Clinical cancer research 1997-05, Vol.3 (5), p.661-667
Hauptverfasser: ALPERT, L. C, SCHECTER, R. L, BERRY, D. A, MELNYCHUK, D, PETERS, W. P, CARUSO, J. A, TOWNSEND, A. J, BATIST, G
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Sprache:eng
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