Relation of glutathione S-transferase alpha and mu isoforms to response to therapy in human breast cancer
Glutathione S-transferase (GST) represents a multifunctional enzyme family consisting of four known cytosolic isoforms (alpha, mu, pi, and Phi) that detoxify a variety of xenobiotic chemicals and may confer resistance to both chemotherapeutic drugs and carcinogens in various experimental models. GST...
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Veröffentlicht in: | Clinical cancer research 1997-05, Vol.3 (5), p.661-667 |
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