Site-Specific Gene Delivery in vivo through Engineered Sendai Viral Envelopes

Inspite of several stimulating developments in gene therapy, the formulation of a targeted gene delivery "vector" is still far from ideal. We have demonstrated the potential of reconstituted Sendai viral envelopes containing only the fusion glycoprotein (F-virosomes) in targeted delivery o...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1998-09, Vol.95 (20), p.11886-11890
Hauptverfasser:	Ramani, Komal, Hassan, Quamarul, Venkaiah, Betapudi, Hasnain, Seyed E., Sarkar, Debi P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological Sciences Cells Chloramphenicol O-Acetyltransferase - genetics Chromosomes - genetics DNA DNA - administration & dosage DNA - genetics Female Gene Expression Genes Genes, Reporter Genetic Engineering Genetic Vectors Genetics Hepatocytes Liver Liver - cytology Liver - enzymology Liver cells Luciferases - genetics Membrane Fusion Mice Mice, Inbred BALB C Plasmids Polymerase chain reaction Respirovirus - genetics Reverse transcriptase polymerase chain reaction Viruses
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