High dose chemotherapy with thiotepa, carboplatin, VP16 and autologous stem cell transplantation in treatment of malignant brain tumors with poor prognosis. Results of a mono-center pilot study

More than half of the children and adolescents with malignant brain tumors will relapse following initial therapy. Irrespective of the therapeutic modalities the prognosis of patients with recurrent or metastatic brain tumors is still poor. New strategies such as high dose chemotherapy (HDCT) with a...

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Veröffentlicht in:	Klinische Pädiatrie 1998-07, Vol.210 (4), p.248
Hauptverfasser:	Fleischhack, G, Pöpping, K, Hasan, C, Utsch, B, Jüttner, J, Bode, U
Format:	Artikel
Sprache:	ger
Schlagworte:	Adolescent Adult Antineoplastic Combined Chemotherapy Protocols - adverse effects Antineoplastic Combined Chemotherapy Protocols - therapeutic use Brain Neoplasms - drug therapy Brain Neoplasms - mortality Brain Neoplasms - pathology Brain Neoplasms - secondary Carboplatin - administration & dosage Carboplatin - adverse effects Child Child, Preschool Dose-Response Relationship, Drug Drug Administration Schedule Etoposide - administration & dosage Etoposide - adverse effects Female Hematopoietic Stem Cell Transplantation Humans Male Neoplasm Recurrence, Local - drug therapy Neoplasm Recurrence, Local - mortality Neoplasm Recurrence, Local - pathology Neoplasm, Residual - drug therapy Neoplasm, Residual - mortality Neoplasm, Residual - pathology Pilot Projects Prognosis Salvage Therapy Survival Rate Thiotepa - administration & dosage Thiotepa - adverse effects
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