Pharmacokinetic interactions of artemether and pyrimethamine in healthy male thais

The pharmacokinetics of a single oral dose of artemether (300 mg) and pyrimethamine (100 mg) given as each individual drug alone or as a drug combination (artemether 300 mg plus pyrimethamine 100 mg), were investigated in 8 healthy male Thai volunteers. Both artemether and pyrimethamine were rapidly...

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Veröffentlicht in:	Southeast Asian journal of tropical medicine and public health 1998-03, Vol.29 (1), p.18-23
Hauptverfasser:	TAN-ARIYA, P, NA-BANGCHANG, K, UBALEE, R, THANAVIBUL, A, THIPWANGKOSOL, P, KARBWANG, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antibiotics. Antiinfectious agents. Antiparasitic agents Antimalarials - blood Antimalarials - pharmacokinetics Antiparasitic agents Artemisinins Biological and medical sciences Cross-Over Studies Drug Interactions Humans Male Medical sciences Pharmacology. Drug treatments Pyrimethamine - blood Pyrimethamine - pharmacokinetics Sesquiterpenes - blood Sesquiterpenes - pharmacokinetics Thailand Tropical medicine
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