[40] Construction of MDR1 adeno-associated virus vectors for gene therapy

This chapter discusses the construction of multidrug resistance gene (MDR1) adeno-associated virus vectors (AAV) for gene therapy. Because of the large size of the MDR1 cDNA, the AAV coding sequences must be deleted prior to the insertion of MDR1 between the inverted terminal repeats (ITRs) of recom...

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Veröffentlicht in:	Methods in Enzymology 1998, Vol.292, p.538-545
1. Verfasser:	Baudard, Marion
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals ATP Binding Cassette Transporter, Subfamily B, Member 1 - biosynthesis ATP Binding Cassette Transporter, Subfamily B, Member 1 - genetics Cell Line Cell Survival - drug effects Cytotoxins - toxicity Dependovirus - genetics Drug Resistance, Multiple - genetics Genetic Therapy - methods Genetic Vectors Humans
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