Statistical modeling of carcinogenic risks in dogs that inhaled 238PuO2

Combined analyses of data on 260 life-span beagle dogs that inhaled 238PuO2 at the Inhalation Toxicology Research Institute (ITRI) and at Pacific Northwest National Laboratory (PNNL) were conducted. The hazard functions (age-specific risks) for incidence of lung, bone and liver tumors were modeled a...

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Veröffentlicht in:	Radiation research 1998-07, Vol.150 (1), p.66-82
Hauptverfasser:	GILBERT, E. S, GRIFFITH, W. C, BOECKER, B. B, DAGLE, G. E, GUILMETTE, R. A, HAHN, F. F, MUGGENBURG, B. A, PARK, J. F, WATSON, C. R
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Inhalation Animals Biological and medical sciences Bone Neoplasms - etiology Carcinogenesis, carcinogens and anticarcinogens Data Interpretation, Statistical Dogs Dose-Response Relationship, Radiation Female Linear Models Liver Neoplasms, Experimental - etiology Lung Neoplasms - etiology Male Medical sciences Models, Statistical Neoplasms, Radiation-Induced - etiology Physical agents Plutonium - administration & dosage Plutonium - toxicity Proportional Hazards Models Risk Factors Tumors
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