Stepwise intravenous infusion of apomorphine to determine the therapeutic window in patients with Parkinson's disease

A new experimental strategy was applied to determine the concentration-effect relation and the therapeutic window of apomorphine in individual patients with Parkinson's disease. Apomorphine was administered by a stepwise intravenous infusion. The infusion rate was increased by 10 micrograms/kg/...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Clinical neuropharmacology 1998-05, Vol.21 (3), p.152-158
Hauptverfasser:	VAN LAAR, T, VAN DER GEEST, R, DANHOF, M, BODDE, H. E, GOOSSENS, P. H, ROOS, R. A. C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Anticonvulsants. Antiepileptics. Antiparkinson agents Antiparkinson Agents - administration & dosage Antiparkinson Agents - adverse effects Antiparkinson Agents - pharmacokinetics Apomorphine - administration & dosage Apomorphine - adverse effects Apomorphine - pharmacokinetics Area Under Curve Biological and medical sciences Dopamine Agonists - administration & dosage Dopamine Agonists - adverse effects Dopamine Agonists - pharmacokinetics Drug Administration Schedule Dyskinesia, Drug-Induced Female Humans Infusions, Intravenous Male Medical sciences Middle Aged Neuropharmacology Parkinson Disease - drug therapy Pharmacology. Drug treatments Reaction Time - drug effects Treatment Outcome Tremor - drug therapy
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!