Alcohol consumption and the 5-year incidence of age-related maculopathy: The beaver dam eye study
This study evaluated alcohol consumption as a risk factor for incidence of age-related maculopathy (ARM). Persons aged 43 to 86 years in 1988 in Beaver Dam, Wisconsin, were examined from 1988 through 1990 and 1993 through 1995, n = 3684. The presence and severity of ARM at both examinations were det...
Gespeichert in:
| Veröffentlicht in: | Ophthalmology (Rochester, Minn.) Minn.), 1998-05, Vol.105 (5), p.789-794 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 794 |
|---|---|
| container_issue | 5 |
| container_start_page | 789 |
| container_title | Ophthalmology (Rochester, Minn.) |
| container_volume | 105 |
| creator | Moss, Scot E Klein, Ronald Klein, Barbara E.K Jensen, Susan C Meuer, Stacy M |
| description | This study evaluated alcohol consumption as a risk factor for incidence of age-related maculopathy (ARM).
Persons aged 43 to 86 years in 1988 in Beaver Dam, Wisconsin, were examined from 1988 through 1990 and 1993 through 1995, n = 3684. The presence and severity of ARM at both examinations were determined from gradings of stereoscopic fundus photographs using the Wisconsin Age-related Maculopathy Classification System. Alcohol consumption was determined by self-report.
Men drinking at least 78 g/week of alcohol from beer had a higher 5-year age-adjusted incidence of early ARM (10.6%) than did men who did not drink beer (6.9%), but the test for trend was only borderline significant (
P = 0.08). However, incidence of soft indistinct drusen (
P = 0.01), increased drusen area (
P < 0.01), and confluent drusen (
P = 0.02) are all associated with beer drinking in men. Increased retinal pigment and retinal pigment epithelial depigmentation are not associated with beer drinking in men or women nor are any lesions associated with total alcohol consumption or consumption from liquor or wine in either men or women.
Except for an association of beer drinking with retinal drusen in men, consumption of alcoholic beverages is not likely to be an important risk factor for incidence of ARM. |
| doi_str_mv | 10.1016/S0161-6420(98)95016-3 |
| format | Article |
| fullrecord | <record><control><sourceid>elsevier_pubme</sourceid><recordid>TN_cdi_pubmed_primary_9593377</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0161642098950163</els_id><sourcerecordid>S0161642098950163</sourcerecordid><originalsourceid>FETCH-LOGICAL-e231t-32ed804e6f4f16c0211ca13dc71922bf91c67fb9219190274e3787e6c205b8893</originalsourceid><addsrcrecordid>eNo9kElLBDEQhYMo4zj6EwZy1EM0lXQnHS8igxsMeHA8h3RS7bT0Ri8D_e_tWfBSRfGqivc-QpbA74GDeviaCjAVCX5rkjsTTyOTZ2QOcWRYpEGek_n_yiW56rpfzrlSMpqRmYmNlFrPiXsufL2tC-rrqhvKps_riroq0H6LNGYjupbmlc8DVh5pnVH3g6zFwvUYaOn8UNSN67fjI91MBym6HbY0uJLiiLTrhzBek4vMFR3enPqCfL--bFbvbP359rF6XjMUEnomBYaER6iyKAPluQDwDmTwGowQaWbAK52lRoABw4WOUOpEo_KCx2mSGLkgy-PfZkhLDLZp89K1oz1FnfSno46TiV2Ore18vk8V8hZ9b0OdW-B2z9Ye2No9OGsSe2BrpfwDYn5qQA</addsrcrecordid><sourcetype>Index Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Alcohol consumption and the 5-year incidence of age-related maculopathy: The beaver dam eye study</title><source>MEDLINE</source><source>ScienceDirect Journals (5 years ago - present)</source><creator>Moss, Scot E ; Klein, Ronald ; Klein, Barbara E.K ; Jensen, Susan C ; Meuer, Stacy M</creator><creatorcontrib>Moss, Scot E ; Klein, Ronald ; Klein, Barbara E.K ; Jensen, Susan C ; Meuer, Stacy M</creatorcontrib><description>This study evaluated alcohol consumption as a risk factor for incidence of age-related maculopathy (ARM).
Persons aged 43 to 86 years in 1988 in Beaver Dam, Wisconsin, were examined from 1988 through 1990 and 1993 through 1995, n = 3684. The presence and severity of ARM at both examinations were determined from gradings of stereoscopic fundus photographs using the Wisconsin Age-related Maculopathy Classification System. Alcohol consumption was determined by self-report.
Men drinking at least 78 g/week of alcohol from beer had a higher 5-year age-adjusted incidence of early ARM (10.6%) than did men who did not drink beer (6.9%), but the test for trend was only borderline significant (
P = 0.08). However, incidence of soft indistinct drusen (
P = 0.01), increased drusen area (
P < 0.01), and confluent drusen (
P = 0.02) are all associated with beer drinking in men. Increased retinal pigment and retinal pigment epithelial depigmentation are not associated with beer drinking in men or women nor are any lesions associated with total alcohol consumption or consumption from liquor or wine in either men or women.
Except for an association of beer drinking with retinal drusen in men, consumption of alcoholic beverages is not likely to be an important risk factor for incidence of ARM.</description><identifier>ISSN: 0161-6420</identifier><identifier>EISSN: 1549-4713</identifier><identifier>DOI: 10.1016/S0161-6420(98)95016-3</identifier><identifier>PMID: 9593377</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Alcohol Drinking - adverse effects ; Disease Progression ; Female ; Humans ; Incidence ; Macular Degeneration - epidemiology ; Macular Degeneration - etiology ; Male ; Middle Aged ; Prospective Studies ; Retinal Drusen - epidemiology ; Retinal Drusen - etiology ; Risk Factors ; Wisconsin - epidemiology</subject><ispartof>Ophthalmology (Rochester, Minn.), 1998-05, Vol.105 (5), p.789-794</ispartof><rights>1998 American Academy of Ophthalmology, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/S0161-6420(98)95016-3$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9593377$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Moss, Scot E</creatorcontrib><creatorcontrib>Klein, Ronald</creatorcontrib><creatorcontrib>Klein, Barbara E.K</creatorcontrib><creatorcontrib>Jensen, Susan C</creatorcontrib><creatorcontrib>Meuer, Stacy M</creatorcontrib><title>Alcohol consumption and the 5-year incidence of age-related maculopathy: The beaver dam eye study</title><title>Ophthalmology (Rochester, Minn.)</title><addtitle>Ophthalmology</addtitle><description>This study evaluated alcohol consumption as a risk factor for incidence of age-related maculopathy (ARM).
Persons aged 43 to 86 years in 1988 in Beaver Dam, Wisconsin, were examined from 1988 through 1990 and 1993 through 1995, n = 3684. The presence and severity of ARM at both examinations were determined from gradings of stereoscopic fundus photographs using the Wisconsin Age-related Maculopathy Classification System. Alcohol consumption was determined by self-report.
Men drinking at least 78 g/week of alcohol from beer had a higher 5-year age-adjusted incidence of early ARM (10.6%) than did men who did not drink beer (6.9%), but the test for trend was only borderline significant (
P = 0.08). However, incidence of soft indistinct drusen (
P = 0.01), increased drusen area (
P < 0.01), and confluent drusen (
P = 0.02) are all associated with beer drinking in men. Increased retinal pigment and retinal pigment epithelial depigmentation are not associated with beer drinking in men or women nor are any lesions associated with total alcohol consumption or consumption from liquor or wine in either men or women.
Except for an association of beer drinking with retinal drusen in men, consumption of alcoholic beverages is not likely to be an important risk factor for incidence of ARM.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Alcohol Drinking - adverse effects</subject><subject>Disease Progression</subject><subject>Female</subject><subject>Humans</subject><subject>Incidence</subject><subject>Macular Degeneration - epidemiology</subject><subject>Macular Degeneration - etiology</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Prospective Studies</subject><subject>Retinal Drusen - epidemiology</subject><subject>Retinal Drusen - etiology</subject><subject>Risk Factors</subject><subject>Wisconsin - epidemiology</subject><issn>0161-6420</issn><issn>1549-4713</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kElLBDEQhYMo4zj6EwZy1EM0lXQnHS8igxsMeHA8h3RS7bT0Ri8D_e_tWfBSRfGqivc-QpbA74GDeviaCjAVCX5rkjsTTyOTZ2QOcWRYpEGek_n_yiW56rpfzrlSMpqRmYmNlFrPiXsufL2tC-rrqhvKps_riroq0H6LNGYjupbmlc8DVh5pnVH3g6zFwvUYaOn8UNSN67fjI91MBym6HbY0uJLiiLTrhzBek4vMFR3enPqCfL--bFbvbP359rF6XjMUEnomBYaER6iyKAPluQDwDmTwGowQaWbAK52lRoABw4WOUOpEo_KCx2mSGLkgy-PfZkhLDLZp89K1oz1FnfSno46TiV2Ore18vk8V8hZ9b0OdW-B2z9Ye2No9OGsSe2BrpfwDYn5qQA</recordid><startdate>19980501</startdate><enddate>19980501</enddate><creator>Moss, Scot E</creator><creator>Klein, Ronald</creator><creator>Klein, Barbara E.K</creator><creator>Jensen, Susan C</creator><creator>Meuer, Stacy M</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope></search><sort><creationdate>19980501</creationdate><title>Alcohol consumption and the 5-year incidence of age-related maculopathy: The beaver dam eye study</title><author>Moss, Scot E ; Klein, Ronald ; Klein, Barbara E.K ; Jensen, Susan C ; Meuer, Stacy M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-e231t-32ed804e6f4f16c0211ca13dc71922bf91c67fb9219190274e3787e6c205b8893</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Alcohol Drinking - adverse effects</topic><topic>Disease Progression</topic><topic>Female</topic><topic>Humans</topic><topic>Incidence</topic><topic>Macular Degeneration - epidemiology</topic><topic>Macular Degeneration - etiology</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Prospective Studies</topic><topic>Retinal Drusen - epidemiology</topic><topic>Retinal Drusen - etiology</topic><topic>Risk Factors</topic><topic>Wisconsin - epidemiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Moss, Scot E</creatorcontrib><creatorcontrib>Klein, Ronald</creatorcontrib><creatorcontrib>Klein, Barbara E.K</creatorcontrib><creatorcontrib>Jensen, Susan C</creatorcontrib><creatorcontrib>Meuer, Stacy M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><jtitle>Ophthalmology (Rochester, Minn.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Moss, Scot E</au><au>Klein, Ronald</au><au>Klein, Barbara E.K</au><au>Jensen, Susan C</au><au>Meuer, Stacy M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Alcohol consumption and the 5-year incidence of age-related maculopathy: The beaver dam eye study</atitle><jtitle>Ophthalmology (Rochester, Minn.)</jtitle><addtitle>Ophthalmology</addtitle><date>1998-05-01</date><risdate>1998</risdate><volume>105</volume><issue>5</issue><spage>789</spage><epage>794</epage><pages>789-794</pages><issn>0161-6420</issn><eissn>1549-4713</eissn><abstract>This study evaluated alcohol consumption as a risk factor for incidence of age-related maculopathy (ARM).
Persons aged 43 to 86 years in 1988 in Beaver Dam, Wisconsin, were examined from 1988 through 1990 and 1993 through 1995, n = 3684. The presence and severity of ARM at both examinations were determined from gradings of stereoscopic fundus photographs using the Wisconsin Age-related Maculopathy Classification System. Alcohol consumption was determined by self-report.
Men drinking at least 78 g/week of alcohol from beer had a higher 5-year age-adjusted incidence of early ARM (10.6%) than did men who did not drink beer (6.9%), but the test for trend was only borderline significant (
P = 0.08). However, incidence of soft indistinct drusen (
P = 0.01), increased drusen area (
P < 0.01), and confluent drusen (
P = 0.02) are all associated with beer drinking in men. Increased retinal pigment and retinal pigment epithelial depigmentation are not associated with beer drinking in men or women nor are any lesions associated with total alcohol consumption or consumption from liquor or wine in either men or women.
Except for an association of beer drinking with retinal drusen in men, consumption of alcoholic beverages is not likely to be an important risk factor for incidence of ARM.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>9593377</pmid><doi>10.1016/S0161-6420(98)95016-3</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0161-6420 |
| ispartof | Ophthalmology (Rochester, Minn.), 1998-05, Vol.105 (5), p.789-794 |
| issn | 0161-6420 1549-4713 |
| language | eng |
| recordid | cdi_pubmed_primary_9593377 |
| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Adult Aged Aged, 80 and over Alcohol Drinking - adverse effects Disease Progression Female Humans Incidence Macular Degeneration - epidemiology Macular Degeneration - etiology Male Middle Aged Prospective Studies Retinal Drusen - epidemiology Retinal Drusen - etiology Risk Factors Wisconsin - epidemiology |
| title | Alcohol consumption and the 5-year incidence of age-related maculopathy: The beaver dam eye study |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-07T20%3A58%3A37IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-elsevier_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Alcohol%20consumption%20and%20the%205-year%20incidence%20of%20age-related%20maculopathy:%20The%20beaver%20dam%20eye%20study&rft.jtitle=Ophthalmology%20(Rochester,%20Minn.)&rft.au=Moss,%20Scot%20E&rft.date=1998-05-01&rft.volume=105&rft.issue=5&rft.spage=789&rft.epage=794&rft.pages=789-794&rft.issn=0161-6420&rft.eissn=1549-4713&rft_id=info:doi/10.1016/S0161-6420(98)95016-3&rft_dat=%3Celsevier_pubme%3ES0161642098950163%3C/elsevier_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/9593377&rft_els_id=S0161642098950163&rfr_iscdi=true |