Inorganic Pi Increases Neuronal Survival in the Acute Early Phase Following Excitotoxic/Oxidative Insults

: Inorganic phosphate (Pi) plays a vital role in intracellular energy metabolism. Its many effects include stimulation of glucose use, enhancement of high‐energy phosphate concentrations, and modulation of cytosolic free [Ca2+]. Cultured fetal rat cortical neurons constitutively import Pi, and cytos...

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Veröffentlicht in:	Journal of neurochemistry 1998-05, Vol.70 (5), p.1850-1858
Hauptverfasser:	Glinn, Michele, Ni, Binhui, Irwin, Robert P., Kelley, S. W., Lin, Sui‐Zhen, Paul, Steven M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals ATP Biochemistry and metabolism Biological and medical sciences Calcium Cell Survival - drug effects Cells, Cultured Central nervous system Cerebral Cortex - cytology Excitotoxicity Fetal cortical neurons Fundamental and applied biological sciences. Psychology Glutathione Neurons - drug effects Neurons - metabolism Neurons - physiology Neurotoxins - pharmacology Oxidative stress Oxidative Stress - physiology Phosphate transport Phosphorus - pharmacology Rats - embryology Time Factors Vertebrates: nervous system and sense organs
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