Colon carcinoma cells use different mechanisms to escape CD95-mediated apoptosis

CD95(APO-1/Fas) is a cell surface receptor that, when oligomerized by natural ligand, CD95L, or antibody, confers an apoptotic signal to apoptosis-sensitive cells. Whereas CD95 is expressed in every colonocyte of normal colon mucosa, CD95 is down-regulated or lost in the majority of colon carcinomas...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1998-02, Vol.58 (3), p.526-534
Hauptverfasser:	VON REYHER, U, STRÄTER, J, KITTSTEIN, W, GSCHWENDT, M, KRAMMER, P. H, MÖLLER, P
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, Neoplasm - physiology Apoptosis Biological and medical sciences Brefeldin A Carcinoma - metabolism Carcinoma - pathology Cell Transformation, Neoplastic Colonic Neoplasms - metabolism Colonic Neoplasms - pathology Cycloheximide - pharmacology Cyclopentanes - pharmacology Dactinomycin - pharmacology Enzyme Inhibitors - pharmacology Fas Ligand Protein fas Receptor - physiology Gastroenterology. Liver. Pancreas. Abdomen Humans Immunologic Capping - drug effects Interferon-gamma - pharmacology Intestinal Mucosa - cytology Intestinal Mucosa - immunology Medical sciences Membrane Glycoproteins - physiology Nucleic Acid Synthesis Inhibitors - pharmacology Phorbol Esters - pharmacology Protein Kinase C - physiology Protein Synthesis Inhibitors - pharmacology Signal Transduction Staurosporine - pharmacology Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Tetradecanoylphorbol Acetate - pharmacology Tumor Cells, Cultured - drug effects Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!