Mutations in the Nucleotide Binding Domain of the α Subunits of the F1-ATPase from Thermophilic Bacillus PS3 That Affect Cross-Talk between Nucleotide Binding Sites

Inactivation of MF1 (bovine mitochondrial F1-ATPase) with 5‘-p-fluorosulfonylbenzoylethenoadenosine is caused by labeling αY244 [Verburg, J. G., and Allison, W. S. (1990) J. Biol. Chem. 265, 8065−8074]. In the crystal structure [Abrahams, J. P., Leslie, A. G. W., Lutter, R., and Walker, J. E. (1994)...

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