Adaptive Evolution via a Major Gene Effect: Paedomorphosis in the Mexican Axolotl
Although adaptive evolution is thought to depend primarily on mutations of small effect, major gene effects may underlie many of the important differences observed among species in nature. The Mexican axolotl (Ambystoma mexicanum) has a derived mode of development that is characterized by metamorphi...
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| Veröffentlicht in: | Proceedings of the National Academy of Sciences - PNAS 1997-12, Vol.94 (25), p.14185-14189 |
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| container_title | Proceedings of the National Academy of Sciences - PNAS |
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| creator | Voss, S. Randal Shaffer, H. Bradley |
| description | Although adaptive evolution is thought to depend primarily on mutations of small effect, major gene effects may underlie many of the important differences observed among species in nature. The Mexican axolotl (Ambystoma mexicanum) has a derived mode of development that is characterized by metamorphic failure (paedomorphosis), an adaptation for an entirely aquatic life cycle. By using an interspecific crossing design and genetic linkage analysis, a major quantitative trait locus for expression of metamorphosis was identified in a local map of amplified fragment length polymorphisms. These data are consistent with a major gene hypothesis for the evolution of paedomorphosis in A. mexicanum. |
| doi_str_mv | 10.1073/pnas.94.25.14185 |
| format | Article |
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| source | Jstor Complete Legacy; PubMed Central; Alma/SFX Local Collection; Free Full-Text Journals in Chemistry |
| subjects | Alleles Ambystoma mexicanum Biological Sciences Biology Ecological genetics Evolution Evolutionary genetics Gels Genes Genetic loci Genotypes Metamorphosis Phenotypes Quantitative trait loci Reptiles & amphibians |
| title | Adaptive Evolution via a Major Gene Effect: Paedomorphosis in the Mexican Axolotl |
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