PTEN/MMAC1 mutations in endometrial cancers

Endometrial carcinomas represent the most common gynecological cancer in the United States, yet the molecular genetic events that underlie the development of these tumors remain obscure. Chromosome 10 is implicated in the pathogenesis of endometrial carcinoma based on loss of heterozygosity (LOH), c...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1997-11, Vol.57 (21), p.4736-4738
Hauptverfasser:	RISINGER, J. I, HAYES, A. K, BERCHUCK, A, BARRETT, J. C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - genetics Biological and medical sciences Chromosomes, Human, Pair 10 - genetics Endometrial Neoplasms - genetics Female Female genital diseases Gene Deletion Genes, Tumor Suppressor - genetics Gynecology. Andrology. Obstetrics Humans Medical sciences Microsatellite Repeats - genetics Mutation - genetics Tumors
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