Defective platelet activation in G alpha(q)-deficient mice

Platelets are small disc-shaped cell fragments which undergo a rapid transformation when they encounter vascular damage. They become more spherical and extrude pseudopodia, their fibrinogen receptors are activated, causing them to aggregate, they release their granule contents, and eventually form a...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nature (London) 1997-09, Vol.389 (6647), p.183
Hauptverfasser:	Offermanns, S, Toombs, C F, Hu, Y H, Simon, M I
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Calcium - metabolism Enzyme Activation GTP-Binding Proteins - deficiency GTP-Binding Proteins - genetics GTP-Binding Proteins - physiology Hemorrhage - etiology In Vitro Techniques Inositol 1,4,5-Trisphosphate - metabolism Mice Mice, Inbred C57BL Mutation Platelet Activation - drug effects Platelet Activation - physiology Signal Transduction Thromboembolism - chemically induced Type C Phospholipases - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!