Angiotensinogen Antisense Oligonucleotides and Fluid Intake

The effectiveness of antisense oligonucleotides (ODNs) to angiotensinogen on intracerebrovenricularly injected renin induced thirst was investigated. As a corollary, information would be gained about the role of centrally synthesised angiotensinogen in the neural mechanisms subserving water drinking...

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Veröffentlicht in:	Clinical and experimental hypertension (1993) 1997, Vol.19 (5-6), p.993-1007
Hauptverfasser:	Sinnayah, P., McKinley, M. J., Coghlan, J. P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin II Angiotensin II - administration & dosage Angiotensinogen Angiotensinogen - antagonists & inhibitors Angiotensinogen - genetics Angiotensinogen - physiology Animals Antisense oligonucleotide Base Sequence Carbachol - administration & dosage Drinking - drug effects Drinking - physiology Injections, Intraventricular Isoproterenol - administration & dosage Male Oligonucleotides, Antisense - administration & dosage Oligonucleotides, Antisense - genetics Oligonucleotides, Antisense - pharmacology Polyethylene Glycols - administration & dosage Rats Rats, Sprague-Dawley Renin - administration & dosage RNA, Messenger - genetics Water Deprivation Water Intake
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