A nidulans bronchial aspergillosis after treatment of low-grade lymphoma with fludarabine

Pulmonary aspergillosis is a common complication in neutropenic patients. The most important fungus is Aspergillus fumigatus. We report a case of invasive pulmonary aspergillosis due to Aspergillus nidulans secondary to fludarabine therapy. There are few cases of pulmonary aspergillosis due to Asper...

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Veröffentlicht in:La revue de medecine interne 1997, Vol.18 (3), p.235
Hauptverfasser: Peyrade, F, Boscagli, A, Roa, M, Taillan, B, Gary-Toussain, M, Dujardin, P
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container_title La revue de medecine interne
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creator Peyrade, F
Boscagli, A
Roa, M
Taillan, B
Gary-Toussain, M
Dujardin, P
description Pulmonary aspergillosis is a common complication in neutropenic patients. The most important fungus is Aspergillus fumigatus. We report a case of invasive pulmonary aspergillosis due to Aspergillus nidulans secondary to fludarabine therapy. There are few cases of pulmonary aspergillosis due to Aspergillus nidulans (one chronic necrotizing pulmonary aspergillosis, one aspergilloma). Fludarabine induces a marked decreased of CD4 lymphocyte count responsible for opportunistic infections. It is the first case of aspergillosis after fludarabine therapy and the occurrence of such infection must be considered after purine analog therapy.
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subjects Antineoplastic Agents - adverse effects
Aspergillosis - etiology
Aspergillosis - microbiology
Bronchial Diseases - etiology
Bronchial Diseases - microbiology
Humans
Lymphoma, Non-Hodgkin - drug therapy
Male
Vidarabine - adverse effects
Vidarabine - analogs & derivatives
title A nidulans bronchial aspergillosis after treatment of low-grade lymphoma with fludarabine
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