Dose responses from inhaled monodisperse aerosols of 244Cm2O3 in the lung, liver and skeleton of F344 rats and comparison with 239PuO2

The purpose of this study was to obtain information on the alpha-particle dose-response relationship of 244Cm in rats. Rats were exposed briefly by inhalation to graded levels of monodisperse aerosols of 244Cm2O3 heat-treated at 1150 degrees C. The initial lung burden (ILB) of each animal was determ...

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Veröffentlicht in:	Radiation research 1997-05, Vol.147 (5), p.598-612
Hauptverfasser:	LUNDGREN, D. L, HAHN, F. F, CARLTON, W. W, GRIFFITH, W. C, GUILMETTE, R. A, GILLETT, N. A
Format:	Artikel
Sprache:	eng
Schlagworte:	Aerosols Animals Biological and medical sciences Biological effects of radiation Body Burden Bone and Bones - radiation effects Bone Neoplasms - etiology Curium - administration & dosage Curium - pharmacokinetics Dose-Response Relationship, Radiation Female Fundamental and applied biological sciences. Psychology Leukemia, Radiation-Induced Liver - radiation effects Liver Neoplasms - etiology Lung - radiation effects Lung Neoplasms - etiology Male Neoplasms, Radiation-Induced Osteosarcoma - diagnostic imaging Osteosarcoma - etiology Plutonium Radiocontamination Radiography Rats Rats, Inbred F344 Tissues, organs and organisms biophysics
Online-Zugang:	Volltext
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