Thrombospondin 1 and type I repeat peptides of thrombospondin 1 specifically induce apoptosis of endothelial cells

Thrombospondin 1 (TSP1) inhibits angiogenesis and modulates endothelial cell adhesion, motility, and growth. The antiproliferative activity of TSP1 is mimicked by synthetic peptides derived from the type I repeats of TSP1 that antagonize fibroblast growth factor 2 and activate latent transforming gr...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1997-05, Vol.57 (9), p.1735-1742
Hauptverfasser:	GUO, N.-H, KRUTZSCH, H. C, INMAN, J. K, ROBERTS, D. D
Format:	Artikel
Sprache:	eng
Schlagworte:	Ageing, cell death Amino Acid Sequence Animals Apoptosis Biological and medical sciences Cattle Cell Adhesion Cell Division - drug effects Cell physiology Cells, Cultured DNA Fragmentation Endothelium, Vascular - cytology Extracellular Matrix - physiology Fibronectins - physiology Fundamental and applied biological sciences. Psychology Membrane Glycoproteins - chemistry Membrane Glycoproteins - pharmacology Molecular and cellular biology Molecular Sequence Data Peptides - chemistry Peptides - pharmacology Phosphorylation Protein Kinase C - physiology Repetitive Sequences, Nucleic Acid Tetradecanoylphorbol Acetate - pharmacology Thrombospondins Transforming Growth Factor beta - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!