Assessment of radioisotopic micturating cystography for the diagnosis of vesicoureteric reflux in renal transplant recipients with acute pyelonephritis
The gold standard for documenting vesicoureteric reflux is direct (retrograde) micturating cystography (MC). In children, radioisotopic MC has been advocated for increased sensitivity and lesser radiation exposure. In renal transplant recipients, where reflux can induce acute pyelonephritis, this te...
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Veröffentlicht in: | Nephrology, dialysis, transplantation dialysis, transplantation, 1997, Vol.12 (1), p.67-70 |
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container_title | Nephrology, dialysis, transplantation |
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creator | CANIVET, E WAMPACH, H BRANDT, B TOUPANCE, O LAVAUD, S LARDENNOIS, B LIEHN, J.-C CHANARD, J |
description | The gold standard for documenting vesicoureteric reflux is direct (retrograde) micturating cystography (MC). In children, radioisotopic MC has been advocated for increased sensitivity and lesser radiation exposure. In renal transplant recipients, where reflux can induce acute pyelonephritis, this technique has not been evaluated. The aim of this study was to assess the radioisotopic technique in these patients.
Seventeen renal transplant recipients had developed acute pyelonephritis following the surgical grafting procedure. They were investigated using both MC techniques. Radioisotopic MC was performed using 99mTc-pertechnetate.
Reflux was documented in nine patients by radioisotopic MC but in only seven with the conventional technique. All negative patients remained symptom free after the pyelonephritis was cured and it was assumed that they had no reflux. Consequently, using the radioisotopic MC as gold standard, the conventional X-ray technique had a sensitivity of 78% and a specificity of 100%.
Direct radioisotopic MC allowing continuous cystogram recording is more accurate than conventional X-ray MC for the diagnosis of vesicoureteric reflux in transplanted patients with acute pyelonephritis. |
doi_str_mv | 10.1093/ndt/12.1.67 |
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Seventeen renal transplant recipients had developed acute pyelonephritis following the surgical grafting procedure. They were investigated using both MC techniques. Radioisotopic MC was performed using 99mTc-pertechnetate.
Reflux was documented in nine patients by radioisotopic MC but in only seven with the conventional technique. All negative patients remained symptom free after the pyelonephritis was cured and it was assumed that they had no reflux. Consequently, using the radioisotopic MC as gold standard, the conventional X-ray technique had a sensitivity of 78% and a specificity of 100%.
Direct radioisotopic MC allowing continuous cystogram recording is more accurate than conventional X-ray MC for the diagnosis of vesicoureteric reflux in transplanted patients with acute pyelonephritis.</description><identifier>ISSN: 0931-0509</identifier><identifier>EISSN: 1460-2385</identifier><identifier>DOI: 10.1093/ndt/12.1.67</identifier><identifier>PMID: 9027775</identifier><identifier>CODEN: NDTREA</identifier><language>eng</language><publisher>Oxford: Oxford University Press</publisher><subject>Acute Disease ; Adult ; Biological and medical sciences ; Child ; Evaluation Studies as Topic ; False Negative Reactions ; False Positive Reactions ; Female ; Humans ; Kidney Transplantation - adverse effects ; Kidney Transplantation - diagnostic imaging ; Male ; Medical sciences ; Pyelonephritis - diagnostic imaging ; Pyelonephritis - etiology ; Radiation Dosage ; Radiography ; Radionuclide Imaging ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Surgery of the urinary system ; Urinary Bladder - diagnostic imaging ; Vesico-Ureteral Reflux - diagnostic imaging ; Vesico-Ureteral Reflux - etiology</subject><ispartof>Nephrology, dialysis, transplantation, 1997, Vol.12 (1), p.67-70</ispartof><rights>1997 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,4010,27902,27903,27904</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2588768$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9027775$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>CANIVET, E</creatorcontrib><creatorcontrib>WAMPACH, H</creatorcontrib><creatorcontrib>BRANDT, B</creatorcontrib><creatorcontrib>TOUPANCE, O</creatorcontrib><creatorcontrib>LAVAUD, S</creatorcontrib><creatorcontrib>LARDENNOIS, B</creatorcontrib><creatorcontrib>LIEHN, J.-C</creatorcontrib><creatorcontrib>CHANARD, J</creatorcontrib><title>Assessment of radioisotopic micturating cystography for the diagnosis of vesicoureteric reflux in renal transplant recipients with acute pyelonephritis</title><title>Nephrology, dialysis, transplantation</title><addtitle>Nephrol Dial Transplant</addtitle><description>The gold standard for documenting vesicoureteric reflux is direct (retrograde) micturating cystography (MC). In children, radioisotopic MC has been advocated for increased sensitivity and lesser radiation exposure. In renal transplant recipients, where reflux can induce acute pyelonephritis, this technique has not been evaluated. The aim of this study was to assess the radioisotopic technique in these patients.
Seventeen renal transplant recipients had developed acute pyelonephritis following the surgical grafting procedure. They were investigated using both MC techniques. Radioisotopic MC was performed using 99mTc-pertechnetate.
Reflux was documented in nine patients by radioisotopic MC but in only seven with the conventional technique. All negative patients remained symptom free after the pyelonephritis was cured and it was assumed that they had no reflux. Consequently, using the radioisotopic MC as gold standard, the conventional X-ray technique had a sensitivity of 78% and a specificity of 100%.
Direct radioisotopic MC allowing continuous cystogram recording is more accurate than conventional X-ray MC for the diagnosis of vesicoureteric reflux in transplanted patients with acute pyelonephritis.</description><subject>Acute Disease</subject><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Child</subject><subject>Evaluation Studies as Topic</subject><subject>False Negative Reactions</subject><subject>False Positive Reactions</subject><subject>Female</subject><subject>Humans</subject><subject>Kidney Transplantation - adverse effects</subject><subject>Kidney Transplantation - diagnostic imaging</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Pyelonephritis - diagnostic imaging</subject><subject>Pyelonephritis - etiology</subject><subject>Radiation Dosage</subject><subject>Radiography</subject><subject>Radionuclide Imaging</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Surgery of the urinary system</subject><subject>Urinary Bladder - diagnostic imaging</subject><subject>Vesico-Ureteral Reflux - diagnostic imaging</subject><subject>Vesico-Ureteral Reflux - etiology</subject><issn>0931-0509</issn><issn>1460-2385</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kM1LAzEQxYMotX6cPAs5eN2abJLN5ljELxC86Fmm2aSNbDchk1X7l_jvumLx9AZ-8-bxhpALzhacGXE9dOWa1wu-aPQBmXPZsKoWrTok84nyiilmjskJ4jtjzNRaz8jMsEm1mpPvJaJD3Lqh0Ohphi7EgLHEFCzdBlvGDCUMa2p3WOI6Q9rsqI-Zlo2jXYD1EDHgr_XDYbBxzK64PHmz8_34RcMwTQP0tGQYMPUw5WRnQwpTItLPUDYU7FgcTTvXx8GlTQ4l4Bk58tCjO9_rKXm9u325eaienu8fb5ZPVaqFKpVlkredNKrR3ksplQajBe-4ZNaBFR58I2qx8qDrummgM7JVykvOV8Y0nROn5PLvbhpXW9e9pRy2kHdv-wdN_GrPAS30fmphA_6v1aptddOKHzM6eXM</recordid><startdate>1997</startdate><enddate>1997</enddate><creator>CANIVET, E</creator><creator>WAMPACH, H</creator><creator>BRANDT, B</creator><creator>TOUPANCE, O</creator><creator>LAVAUD, S</creator><creator>LARDENNOIS, B</creator><creator>LIEHN, J.-C</creator><creator>CHANARD, J</creator><general>Oxford University Press</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope></search><sort><creationdate>1997</creationdate><title>Assessment of radioisotopic micturating cystography for the diagnosis of vesicoureteric reflux in renal transplant recipients with acute pyelonephritis</title><author>CANIVET, E ; WAMPACH, H ; BRANDT, B ; TOUPANCE, O ; LAVAUD, S ; LARDENNOIS, B ; LIEHN, J.-C ; CHANARD, J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p235t-c0418d49567ff44457a9731d140ceac3faf6323bfa72266ad94855f411b996de3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>Acute Disease</topic><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Child</topic><topic>Evaluation Studies as Topic</topic><topic>False Negative Reactions</topic><topic>False Positive Reactions</topic><topic>Female</topic><topic>Humans</topic><topic>Kidney Transplantation - adverse effects</topic><topic>Kidney Transplantation - diagnostic imaging</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Pyelonephritis - diagnostic imaging</topic><topic>Pyelonephritis - etiology</topic><topic>Radiation Dosage</topic><topic>Radiography</topic><topic>Radionuclide Imaging</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Surgery of the urinary system</topic><topic>Urinary Bladder - diagnostic imaging</topic><topic>Vesico-Ureteral Reflux - diagnostic imaging</topic><topic>Vesico-Ureteral Reflux - etiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>CANIVET, E</creatorcontrib><creatorcontrib>WAMPACH, H</creatorcontrib><creatorcontrib>BRANDT, B</creatorcontrib><creatorcontrib>TOUPANCE, O</creatorcontrib><creatorcontrib>LAVAUD, S</creatorcontrib><creatorcontrib>LARDENNOIS, B</creatorcontrib><creatorcontrib>LIEHN, J.-C</creatorcontrib><creatorcontrib>CHANARD, J</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><jtitle>Nephrology, dialysis, transplantation</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>CANIVET, E</au><au>WAMPACH, H</au><au>BRANDT, B</au><au>TOUPANCE, O</au><au>LAVAUD, S</au><au>LARDENNOIS, B</au><au>LIEHN, J.-C</au><au>CHANARD, J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Assessment of radioisotopic micturating cystography for the diagnosis of vesicoureteric reflux in renal transplant recipients with acute pyelonephritis</atitle><jtitle>Nephrology, dialysis, transplantation</jtitle><addtitle>Nephrol Dial Transplant</addtitle><date>1997</date><risdate>1997</risdate><volume>12</volume><issue>1</issue><spage>67</spage><epage>70</epage><pages>67-70</pages><issn>0931-0509</issn><eissn>1460-2385</eissn><coden>NDTREA</coden><abstract>The gold standard for documenting vesicoureteric reflux is direct (retrograde) micturating cystography (MC). In children, radioisotopic MC has been advocated for increased sensitivity and lesser radiation exposure. In renal transplant recipients, where reflux can induce acute pyelonephritis, this technique has not been evaluated. The aim of this study was to assess the radioisotopic technique in these patients.
Seventeen renal transplant recipients had developed acute pyelonephritis following the surgical grafting procedure. They were investigated using both MC techniques. Radioisotopic MC was performed using 99mTc-pertechnetate.
Reflux was documented in nine patients by radioisotopic MC but in only seven with the conventional technique. All negative patients remained symptom free after the pyelonephritis was cured and it was assumed that they had no reflux. Consequently, using the radioisotopic MC as gold standard, the conventional X-ray technique had a sensitivity of 78% and a specificity of 100%.
Direct radioisotopic MC allowing continuous cystogram recording is more accurate than conventional X-ray MC for the diagnosis of vesicoureteric reflux in transplanted patients with acute pyelonephritis.</abstract><cop>Oxford</cop><pub>Oxford University Press</pub><pmid>9027775</pmid><doi>10.1093/ndt/12.1.67</doi><tpages>4</tpages></addata></record> |
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source | Oxford University Press Journals All Titles (1996-Current); MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
subjects | Acute Disease Adult Biological and medical sciences Child Evaluation Studies as Topic False Negative Reactions False Positive Reactions Female Humans Kidney Transplantation - adverse effects Kidney Transplantation - diagnostic imaging Male Medical sciences Pyelonephritis - diagnostic imaging Pyelonephritis - etiology Radiation Dosage Radiography Radionuclide Imaging Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the urinary system Urinary Bladder - diagnostic imaging Vesico-Ureteral Reflux - diagnostic imaging Vesico-Ureteral Reflux - etiology |
title | Assessment of radioisotopic micturating cystography for the diagnosis of vesicoureteric reflux in renal transplant recipients with acute pyelonephritis |
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