Assessment of radioisotopic micturating cystography for the diagnosis of vesicoureteric reflux in renal transplant recipients with acute pyelonephritis

The gold standard for documenting vesicoureteric reflux is direct (retrograde) micturating cystography (MC). In children, radioisotopic MC has been advocated for increased sensitivity and lesser radiation exposure. In renal transplant recipients, where reflux can induce acute pyelonephritis, this te...

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Veröffentlicht in:Nephrology, dialysis, transplantation dialysis, transplantation, 1997, Vol.12 (1), p.67-70
Hauptverfasser: CANIVET, E, WAMPACH, H, BRANDT, B, TOUPANCE, O, LAVAUD, S, LARDENNOIS, B, LIEHN, J.-C, CHANARD, J
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container_end_page 70
container_issue 1
container_start_page 67
container_title Nephrology, dialysis, transplantation
container_volume 12
creator CANIVET, E
WAMPACH, H
BRANDT, B
TOUPANCE, O
LAVAUD, S
LARDENNOIS, B
LIEHN, J.-C
CHANARD, J
description The gold standard for documenting vesicoureteric reflux is direct (retrograde) micturating cystography (MC). In children, radioisotopic MC has been advocated for increased sensitivity and lesser radiation exposure. In renal transplant recipients, where reflux can induce acute pyelonephritis, this technique has not been evaluated. The aim of this study was to assess the radioisotopic technique in these patients. Seventeen renal transplant recipients had developed acute pyelonephritis following the surgical grafting procedure. They were investigated using both MC techniques. Radioisotopic MC was performed using 99mTc-pertechnetate. Reflux was documented in nine patients by radioisotopic MC but in only seven with the conventional technique. All negative patients remained symptom free after the pyelonephritis was cured and it was assumed that they had no reflux. Consequently, using the radioisotopic MC as gold standard, the conventional X-ray technique had a sensitivity of 78% and a specificity of 100%. Direct radioisotopic MC allowing continuous cystogram recording is more accurate than conventional X-ray MC for the diagnosis of vesicoureteric reflux in transplanted patients with acute pyelonephritis.
doi_str_mv 10.1093/ndt/12.1.67
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In children, radioisotopic MC has been advocated for increased sensitivity and lesser radiation exposure. In renal transplant recipients, where reflux can induce acute pyelonephritis, this technique has not been evaluated. The aim of this study was to assess the radioisotopic technique in these patients. Seventeen renal transplant recipients had developed acute pyelonephritis following the surgical grafting procedure. They were investigated using both MC techniques. Radioisotopic MC was performed using 99mTc-pertechnetate. Reflux was documented in nine patients by radioisotopic MC but in only seven with the conventional technique. All negative patients remained symptom free after the pyelonephritis was cured and it was assumed that they had no reflux. Consequently, using the radioisotopic MC as gold standard, the conventional X-ray technique had a sensitivity of 78% and a specificity of 100%. Direct radioisotopic MC allowing continuous cystogram recording is more accurate than conventional X-ray MC for the diagnosis of vesicoureteric reflux in transplanted patients with acute pyelonephritis.</description><identifier>ISSN: 0931-0509</identifier><identifier>EISSN: 1460-2385</identifier><identifier>DOI: 10.1093/ndt/12.1.67</identifier><identifier>PMID: 9027775</identifier><identifier>CODEN: NDTREA</identifier><language>eng</language><publisher>Oxford: Oxford University Press</publisher><subject>Acute Disease ; Adult ; Biological and medical sciences ; Child ; Evaluation Studies as Topic ; False Negative Reactions ; False Positive Reactions ; Female ; Humans ; Kidney Transplantation - adverse effects ; Kidney Transplantation - diagnostic imaging ; Male ; Medical sciences ; Pyelonephritis - diagnostic imaging ; Pyelonephritis - etiology ; Radiation Dosage ; Radiography ; Radionuclide Imaging ; Surgery (general aspects). Transplantations, organ and tissue grafts. 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In children, radioisotopic MC has been advocated for increased sensitivity and lesser radiation exposure. In renal transplant recipients, where reflux can induce acute pyelonephritis, this technique has not been evaluated. The aim of this study was to assess the radioisotopic technique in these patients. Seventeen renal transplant recipients had developed acute pyelonephritis following the surgical grafting procedure. They were investigated using both MC techniques. Radioisotopic MC was performed using 99mTc-pertechnetate. Reflux was documented in nine patients by radioisotopic MC but in only seven with the conventional technique. All negative patients remained symptom free after the pyelonephritis was cured and it was assumed that they had no reflux. Consequently, using the radioisotopic MC as gold standard, the conventional X-ray technique had a sensitivity of 78% and a specificity of 100%. Direct radioisotopic MC allowing continuous cystogram recording is more accurate than conventional X-ray MC for the diagnosis of vesicoureteric reflux in transplanted patients with acute pyelonephritis.</description><subject>Acute Disease</subject><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Child</subject><subject>Evaluation Studies as Topic</subject><subject>False Negative Reactions</subject><subject>False Positive Reactions</subject><subject>Female</subject><subject>Humans</subject><subject>Kidney Transplantation - adverse effects</subject><subject>Kidney Transplantation - diagnostic imaging</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Pyelonephritis - diagnostic imaging</subject><subject>Pyelonephritis - etiology</subject><subject>Radiation Dosage</subject><subject>Radiography</subject><subject>Radionuclide Imaging</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. 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Transplantations, organ and tissue grafts. 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In children, radioisotopic MC has been advocated for increased sensitivity and lesser radiation exposure. In renal transplant recipients, where reflux can induce acute pyelonephritis, this technique has not been evaluated. The aim of this study was to assess the radioisotopic technique in these patients. Seventeen renal transplant recipients had developed acute pyelonephritis following the surgical grafting procedure. They were investigated using both MC techniques. Radioisotopic MC was performed using 99mTc-pertechnetate. Reflux was documented in nine patients by radioisotopic MC but in only seven with the conventional technique. All negative patients remained symptom free after the pyelonephritis was cured and it was assumed that they had no reflux. Consequently, using the radioisotopic MC as gold standard, the conventional X-ray technique had a sensitivity of 78% and a specificity of 100%. Direct radioisotopic MC allowing continuous cystogram recording is more accurate than conventional X-ray MC for the diagnosis of vesicoureteric reflux in transplanted patients with acute pyelonephritis.</abstract><cop>Oxford</cop><pub>Oxford University Press</pub><pmid>9027775</pmid><doi>10.1093/ndt/12.1.67</doi><tpages>4</tpages></addata></record>
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source Oxford University Press Journals All Titles (1996-Current); MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection
subjects Acute Disease
Adult
Biological and medical sciences
Child
Evaluation Studies as Topic
False Negative Reactions
False Positive Reactions
Female
Humans
Kidney Transplantation - adverse effects
Kidney Transplantation - diagnostic imaging
Male
Medical sciences
Pyelonephritis - diagnostic imaging
Pyelonephritis - etiology
Radiation Dosage
Radiography
Radionuclide Imaging
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the urinary system
Urinary Bladder - diagnostic imaging
Vesico-Ureteral Reflux - diagnostic imaging
Vesico-Ureteral Reflux - etiology
title Assessment of radioisotopic micturating cystography for the diagnosis of vesicoureteric reflux in renal transplant recipients with acute pyelonephritis
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