EITS changes following oleic acid induced lung water

We present the results of using electrical impedance tomographic spectroscopy (EITS) to follow the changes in lung water induced by oleic acid. Measurements were made on three goats before and after the injection of oleic acid. In addition to the EITs measurements, lung water was also measured using...

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Veröffentlicht in:Physiological measurement 1996-11, Vol.17 (4A), p.A117-A130
Hauptverfasser: Brown, B H, Flewelling, R, Griffiths, H, Harris, N D, Leathard, A D, Lu, L, Morice, A H, Neufeld, G R, Nopp, P, Wang, W
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container_end_page A130
container_issue 4A
container_start_page A117
container_title Physiological measurement
container_volume 17
creator Brown, B H
Flewelling, R
Griffiths, H
Harris, N D
Leathard, A D
Lu, L
Morice, A H
Neufeld, G R
Nopp, P
Wang, W
description We present the results of using electrical impedance tomographic spectroscopy (EITS) to follow the changes in lung water induced by oleic acid. Measurements were made on three goats before and after the injection of oleic acid. In addition to the EITs measurements, lung water was also measured using a double-indicator technique. Large falls in lung electrical impedance were seen as a result of the increase in lung water but the size of the fall was a function of the frequency at which the measurements were made. These changes have been modelled using the Cole equation. Four-electrode measurements were also made on two extracted porcine lungs and Cole equation modelling carried out following the introduction of saline into the lungs. Results were similar in the two sets of animal experiments.
doi_str_mv 10.1088/0967-3334/17/4A/016
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source MEDLINE; IOP Publishing Journals; Institute of Physics (IOP) Journals - HEAL-Link
subjects Animals
Body Water - metabolism
Electric Impedance
Goats
Humans
In Vitro Techniques
Lung - drug effects
Lung - metabolism
Models, Biological
Oleic Acid - toxicity
Pulmonary Edema - chemically induced
Pulmonary Edema - diagnosis
Pulmonary Edema - metabolism
Respiratory Distress Syndrome, Adult - diagnosis
Swine
Tomography - methods
Ventricular Dysfunction, Left - diagnosis
title EITS changes following oleic acid induced lung water
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