EITS changes following oleic acid induced lung water
We present the results of using electrical impedance tomographic spectroscopy (EITS) to follow the changes in lung water induced by oleic acid. Measurements were made on three goats before and after the injection of oleic acid. In addition to the EITs measurements, lung water was also measured using...
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Veröffentlicht in: | Physiological measurement 1996-11, Vol.17 (4A), p.A117-A130 |
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creator | Brown, B H Flewelling, R Griffiths, H Harris, N D Leathard, A D Lu, L Morice, A H Neufeld, G R Nopp, P Wang, W |
description | We present the results of using electrical impedance tomographic spectroscopy (EITS) to follow the changes in lung water induced by oleic acid. Measurements were made on three goats before and after the injection of oleic acid. In addition to the EITs measurements, lung water was also measured using a double-indicator technique. Large falls in lung electrical impedance were seen as a result of the increase in lung water but the size of the fall was a function of the frequency at which the measurements were made. These changes have been modelled using the Cole equation. Four-electrode measurements were also made on two extracted porcine lungs and Cole equation modelling carried out following the introduction of saline into the lungs. Results were similar in the two sets of animal experiments. |
doi_str_mv | 10.1088/0967-3334/17/4A/016 |
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Measurements were made on three goats before and after the injection of oleic acid. In addition to the EITs measurements, lung water was also measured using a double-indicator technique. Large falls in lung electrical impedance were seen as a result of the increase in lung water but the size of the fall was a function of the frequency at which the measurements were made. These changes have been modelled using the Cole equation. Four-electrode measurements were also made on two extracted porcine lungs and Cole equation modelling carried out following the introduction of saline into the lungs. Results were similar in the two sets of animal experiments.</description><identifier>ISSN: 0967-3334</identifier><identifier>EISSN: 1361-6579</identifier><identifier>DOI: 10.1088/0967-3334/17/4A/016</identifier><identifier>PMID: 9001610</identifier><language>eng</language><publisher>England: IOP Publishing</publisher><subject>Animals ; Body Water - metabolism ; Electric Impedance ; Goats ; Humans ; In Vitro Techniques ; Lung - drug effects ; Lung - metabolism ; Models, Biological ; Oleic Acid - toxicity ; Pulmonary Edema - chemically induced ; Pulmonary Edema - diagnosis ; Pulmonary Edema - metabolism ; Respiratory Distress Syndrome, Adult - diagnosis ; Swine ; Tomography - methods ; Ventricular Dysfunction, Left - diagnosis</subject><ispartof>Physiological measurement, 1996-11, Vol.17 (4A), p.A117-A130</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c376t-ff9eee27f08b063928741224b808330c1cf3c8945cc1488e1a1c0b26c82e2a963</citedby><cites>FETCH-LOGICAL-c376t-ff9eee27f08b063928741224b808330c1cf3c8945cc1488e1a1c0b26c82e2a963</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://iopscience.iop.org/article/10.1088/0967-3334/17/4A/016/pdf$$EPDF$$P50$$Giop$$H</linktopdf><link.rule.ids>314,776,780,27901,27902,53805,53885</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9001610$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Brown, B H</creatorcontrib><creatorcontrib>Flewelling, R</creatorcontrib><creatorcontrib>Griffiths, H</creatorcontrib><creatorcontrib>Harris, N D</creatorcontrib><creatorcontrib>Leathard, A D</creatorcontrib><creatorcontrib>Lu, L</creatorcontrib><creatorcontrib>Morice, A H</creatorcontrib><creatorcontrib>Neufeld, G R</creatorcontrib><creatorcontrib>Nopp, P</creatorcontrib><creatorcontrib>Wang, W</creatorcontrib><title>EITS changes following oleic acid induced lung water</title><title>Physiological measurement</title><addtitle>Physiol Meas</addtitle><description>We present the results of using electrical impedance tomographic spectroscopy (EITS) to follow the changes in lung water induced by oleic acid. Measurements were made on three goats before and after the injection of oleic acid. In addition to the EITs measurements, lung water was also measured using a double-indicator technique. Large falls in lung electrical impedance were seen as a result of the increase in lung water but the size of the fall was a function of the frequency at which the measurements were made. These changes have been modelled using the Cole equation. Four-electrode measurements were also made on two extracted porcine lungs and Cole equation modelling carried out following the introduction of saline into the lungs. Results were similar in the two sets of animal experiments.</description><subject>Animals</subject><subject>Body Water - metabolism</subject><subject>Electric Impedance</subject><subject>Goats</subject><subject>Humans</subject><subject>In Vitro Techniques</subject><subject>Lung - drug effects</subject><subject>Lung - metabolism</subject><subject>Models, Biological</subject><subject>Oleic Acid - toxicity</subject><subject>Pulmonary Edema - chemically induced</subject><subject>Pulmonary Edema - diagnosis</subject><subject>Pulmonary Edema - metabolism</subject><subject>Respiratory Distress Syndrome, Adult - diagnosis</subject><subject>Swine</subject><subject>Tomography - methods</subject><subject>Ventricular Dysfunction, Left - diagnosis</subject><issn>0967-3334</issn><issn>1361-6579</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1996</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1Lw0AQhhdRaq3-AhFyFtLM7G7341hK_YCCB-t52Ux2ayRtQtJS_PemtPSieJph3ved4RnG7hHGCMZkYJVOhRAyQ53JaQaoLtgQhcJUTbS9ZMOz45rddN0XAKLhkwEb2L5VCEMm56_L94Q-_WYVuiTWVVXvy80qqatQUuKpLJJyU-woFEm16-d7vw3tLbuKvurC3amO2MfTfDl7SRdvz6-z6SIlodU2jdGGELiOYHJQwnKjJXIucwNGCCCkKMhYOSFCaUxAjwQ5V2R44N4qMWLiuJfauuvaEF3TlmvffjsEd3iBOwC6A6BD7eTU9VR96uGYanb5OhTnzIm51x-Pelk3Z_GPRa4pYm8e_zb_d_0HeS9v5w</recordid><startdate>19961101</startdate><enddate>19961101</enddate><creator>Brown, B H</creator><creator>Flewelling, R</creator><creator>Griffiths, H</creator><creator>Harris, N D</creator><creator>Leathard, A D</creator><creator>Lu, L</creator><creator>Morice, A H</creator><creator>Neufeld, G R</creator><creator>Nopp, P</creator><creator>Wang, W</creator><general>IOP Publishing</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>19961101</creationdate><title>EITS changes following oleic acid induced lung water</title><author>Brown, B H ; Flewelling, R ; Griffiths, H ; Harris, N D ; Leathard, A D ; Lu, L ; Morice, A H ; Neufeld, G R ; Nopp, P ; Wang, W</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c376t-ff9eee27f08b063928741224b808330c1cf3c8945cc1488e1a1c0b26c82e2a963</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1996</creationdate><topic>Animals</topic><topic>Body Water - metabolism</topic><topic>Electric Impedance</topic><topic>Goats</topic><topic>Humans</topic><topic>In Vitro Techniques</topic><topic>Lung - drug effects</topic><topic>Lung - metabolism</topic><topic>Models, Biological</topic><topic>Oleic Acid - toxicity</topic><topic>Pulmonary Edema - chemically induced</topic><topic>Pulmonary Edema - diagnosis</topic><topic>Pulmonary Edema - metabolism</topic><topic>Respiratory Distress Syndrome, Adult - diagnosis</topic><topic>Swine</topic><topic>Tomography - methods</topic><topic>Ventricular Dysfunction, Left - diagnosis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Brown, B H</creatorcontrib><creatorcontrib>Flewelling, R</creatorcontrib><creatorcontrib>Griffiths, H</creatorcontrib><creatorcontrib>Harris, N D</creatorcontrib><creatorcontrib>Leathard, A D</creatorcontrib><creatorcontrib>Lu, L</creatorcontrib><creatorcontrib>Morice, A H</creatorcontrib><creatorcontrib>Neufeld, G R</creatorcontrib><creatorcontrib>Nopp, P</creatorcontrib><creatorcontrib>Wang, W</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Physiological measurement</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Brown, B H</au><au>Flewelling, R</au><au>Griffiths, H</au><au>Harris, N D</au><au>Leathard, A D</au><au>Lu, L</au><au>Morice, A H</au><au>Neufeld, G R</au><au>Nopp, P</au><au>Wang, W</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>EITS changes following oleic acid induced lung water</atitle><jtitle>Physiological measurement</jtitle><addtitle>Physiol Meas</addtitle><date>1996-11-01</date><risdate>1996</risdate><volume>17</volume><issue>4A</issue><spage>A117</spage><epage>A130</epage><pages>A117-A130</pages><issn>0967-3334</issn><eissn>1361-6579</eissn><abstract>We present the results of using electrical impedance tomographic spectroscopy (EITS) to follow the changes in lung water induced by oleic acid. Measurements were made on three goats before and after the injection of oleic acid. In addition to the EITs measurements, lung water was also measured using a double-indicator technique. Large falls in lung electrical impedance were seen as a result of the increase in lung water but the size of the fall was a function of the frequency at which the measurements were made. These changes have been modelled using the Cole equation. Four-electrode measurements were also made on two extracted porcine lungs and Cole equation modelling carried out following the introduction of saline into the lungs. Results were similar in the two sets of animal experiments.</abstract><cop>England</cop><pub>IOP Publishing</pub><pmid>9001610</pmid><doi>10.1088/0967-3334/17/4A/016</doi></addata></record> |
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subjects | Animals Body Water - metabolism Electric Impedance Goats Humans In Vitro Techniques Lung - drug effects Lung - metabolism Models, Biological Oleic Acid - toxicity Pulmonary Edema - chemically induced Pulmonary Edema - diagnosis Pulmonary Edema - metabolism Respiratory Distress Syndrome, Adult - diagnosis Swine Tomography - methods Ventricular Dysfunction, Left - diagnosis |
title | EITS changes following oleic acid induced lung water |
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