Clinical Assessment of the 1987 American College of Rheumatology Criteria for Rheumatoid Arthritis

The 1987 American College of Rheumatology (ACR) criteria for the classification of rheumatoid arthritis (RA) were clinically assessed. These criteria do not include findings of synovial fluid (SF) analysis and require no exclusion criteria. We have studied sequential patients with arthritis seen in...

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Veröffentlicht in:Scandinavian journal of rheumatology 1996, Vol.25 (5), p.277-281
Hauptverfasser: Levin, R. W., Park, J., Ostrov, B., Reginato, A., Baker, D. G., Bomalaski, J. S., Borofsky, M., Gardiner, M., Leventhal, L., Louthrenoo, W., von Feldt, J., Kolasinski, S., Schumacher, H. R.
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container_end_page 281
container_issue 5
container_start_page 277
container_title Scandinavian journal of rheumatology
container_volume 25
creator Levin, R. W.
Park, J.
Ostrov, B.
Reginato, A.
Baker, D. G.
Bomalaski, J. S.
Borofsky, M.
Gardiner, M.
Leventhal, L.
Louthrenoo, W.
von Feldt, J.
Kolasinski, S.
Schumacher, H. R.
description The 1987 American College of Rheumatology (ACR) criteria for the classification of rheumatoid arthritis (RA) were clinically assessed. These criteria do not include findings of synovial fluid (SF) analysis and require no exclusion criteria. We have studied sequential patients with arthritis seen in four rheumatology centers in the Philadelphia area. Classifications by the ACR criteria were compared with our clinical diagnoses. Two hundred ninety eight patients were evaluated, 113 with RA and 185 with other diagnoses. Classifications as RA by the ACR criteria corresponded to our clinical diagnosis in 95% of the cases, corroborating the high sensitivity previously reported. However, we found a lower specificity (73%) than that reported (89%). False positive classifications as RA were found in 71% of patients with psoriatic arthritis, 48% of patients with SLE, and 31% of patients with gout. The specificity could be improved to 89% by excluding disorders with obvious distinguishing extraarticular features such as psoriasis or by SF findings of monosodium urate crystals. Awareness of these possible sources of confusion will further increase the teaching and epidemiologic value of these useful simplified criteria.
doi_str_mv 10.3109/03009749609104058
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Classifications as RA by the ACR criteria corresponded to our clinical diagnosis in 95% of the cases, corroborating the high sensitivity previously reported. However, we found a lower specificity (73%) than that reported (89%). False positive classifications as RA were found in 71% of patients with psoriatic arthritis, 48% of patients with SLE, and 31% of patients with gout. The specificity could be improved to 89% by excluding disorders with obvious distinguishing extraarticular features such as psoriasis or by SF findings of monosodium urate crystals. 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W.</creatorcontrib><creatorcontrib>Park, J.</creatorcontrib><creatorcontrib>Ostrov, B.</creatorcontrib><creatorcontrib>Reginato, A.</creatorcontrib><creatorcontrib>Baker, D. G.</creatorcontrib><creatorcontrib>Bomalaski, J. S.</creatorcontrib><creatorcontrib>Borofsky, M.</creatorcontrib><creatorcontrib>Gardiner, M.</creatorcontrib><creatorcontrib>Leventhal, L.</creatorcontrib><creatorcontrib>Louthrenoo, W.</creatorcontrib><creatorcontrib>von Feldt, J.</creatorcontrib><creatorcontrib>Kolasinski, S.</creatorcontrib><creatorcontrib>Schumacher, H. R.</creatorcontrib><title>Clinical Assessment of the 1987 American College of Rheumatology Criteria for Rheumatoid Arthritis</title><title>Scandinavian journal of rheumatology</title><addtitle>Scand J Rheumatol</addtitle><description>The 1987 American College of Rheumatology (ACR) criteria for the classification of rheumatoid arthritis (RA) were clinically assessed. These criteria do not include findings of synovial fluid (SF) analysis and require no exclusion criteria. We have studied sequential patients with arthritis seen in four rheumatology centers in the Philadelphia area. Classifications by the ACR criteria were compared with our clinical diagnoses. Two hundred ninety eight patients were evaluated, 113 with RA and 185 with other diagnoses. Classifications as RA by the ACR criteria corresponded to our clinical diagnosis in 95% of the cases, corroborating the high sensitivity previously reported. However, we found a lower specificity (73%) than that reported (89%). False positive classifications as RA were found in 71% of patients with psoriatic arthritis, 48% of patients with SLE, and 31% of patients with gout. The specificity could be improved to 89% by excluding disorders with obvious distinguishing extraarticular features such as psoriasis or by SF findings of monosodium urate crystals. 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source MEDLINE; Taylor & Francis Medical Library - CRKN; Taylor & Francis Journals Complete
subjects Adult
Aged
Arthritis, Rheumatoid - diagnosis
Biological and medical sciences
criteria
Diagnosis, Differential
Diseases of the osteoarticular system
False Positive Reactions
Female
Humans
Inflammatory joint diseases
Male
Medical sciences
Middle Aged
Practice Guidelines as Topic - standards
Prospective Studies
rheumatoid arthritis
Rheumatology - standards
Sensitivity and Specificity
Societies, Medical - standards
synovial fluid
title Clinical Assessment of the 1987 American College of Rheumatology Criteria for Rheumatoid Arthritis
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