Clinical experiences with magnetic drug targeting : A phase I study with 4'-epidoxorubicin in 14 patients with advanced solid tumors

Anticancer drugs reversibly bound to magnetic fluids (ferrofluids) could be concentrated in locally advanced tumors by magnetic fields that are arranged at the tumor surface outside of the organism. If certain requirements are met, systemic toxicity might be minimized, and local tumor efficacy might...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1996-10, Vol.56 (20), p.4686-4693
Hauptverfasser:	LÜBBE, A. S, BERGEMANN, C, HOHENBERGER, P, HAAS, N, SOHR, R, SANDER, B, LEMKE, A.-J, OHLENDORF, D, HUHNT, W, HUHN, D, RIESS, H, SCHRIEVER, F, REICHARDT, P, POSSINGER, K, MATTHIAS, M, DÖRKEN, B, HERRMANN, F, GÜRTLER, R
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Antibiotics, Antineoplastic - administration & dosage Antibiotics, Antineoplastic - adverse effects Antibiotics, Antineoplastic - pharmacokinetics Antineoplastic agents Biological and medical sciences Chemotherapy Drug Delivery Systems Epirubicin - administration & dosage Epirubicin - adverse effects Epirubicin - pharmacokinetics Female Ferritins - blood Humans Iron - blood Magnetics - therapeutic use Male Medical sciences Middle Aged Neoplasms - blood Neoplasms - drug therapy Pharmacology. Drug treatments
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