Ocular Masquerade Syndrome in Lymphoid Blast Crisis of Chronic Myeloid Leukemia
A 56-year-old woman presented with CML in lymphoid blast crisis. Complete remission with no suggestion of CML was achieved with chemotherapy. Twenty-six months later, an isolated ocular anterior chamber relapse of acute leukemia presenting as uveitis (ocular masquerade syndrome) was diagnosed and tr...
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Veröffentlicht in: | Leukemia & lymphoma 1995, Vol.20 (1-2), p.161-163 |
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creator | Lipton, Jeffrey H. McGowan, Hugh D. Payne, David G. |
description | A 56-year-old woman presented with CML in lymphoid blast crisis. Complete remission with no suggestion of CML was achieved with chemotherapy. Twenty-six months later, an isolated ocular anterior chamber relapse of acute leukemia presenting as uveitis (ocular masquerade syndrome) was diagnosed and treated with radiotherapy. Ten months later, a second ocular relapse in the same location was diagnosed and treated with radiotherapy. Two months later, a systemic relapse into second chronic phase was diagnosed and is currently being treated with alpha interferon. Only one previous case of leukemic hypopyon in CML has been reported. This is also the first case of isolated ocular blast crisis relapse in CML to be described. |
doi_str_mv | 10.3109/10428199509054769 |
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Complete remission with no suggestion of CML was achieved with chemotherapy. Twenty-six months later, an isolated ocular anterior chamber relapse of acute leukemia presenting as uveitis (ocular masquerade syndrome) was diagnosed and treated with radiotherapy. Ten months later, a second ocular relapse in the same location was diagnosed and treated with radiotherapy. Two months later, a systemic relapse into second chronic phase was diagnosed and is currently being treated with alpha interferon. Only one previous case of leukemic hypopyon in CML has been reported. This is also the first case of isolated ocular blast crisis relapse in CML to be described.</description><identifier>ISSN: 1042-8194</identifier><identifier>EISSN: 1029-2403</identifier><identifier>DOI: 10.3109/10428199509054769</identifier><identifier>PMID: 8750639</identifier><language>eng</language><publisher>United States: Informa UK Ltd</publisher><subject>Blast Crisis ; Chronic myeloid leukemia ; Cobalt Radioisotopes - therapeutic use ; Eye Neoplasms - pathology ; Eye Neoplasms - radiotherapy ; Eye Neoplasms - secondary ; Eye Neoplasms - therapy ; Female ; Humans ; hypopyon ; Interferon-alpha - therapeutic use ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive - therapy ; masquerade syndrome ; Middle Aged ; ocular leukemia ; Recurrence ; Syndrome ; Uveitis - etiology</subject><ispartof>Leukemia & lymphoma, 1995, Vol.20 (1-2), p.161-163</ispartof><rights>1995 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 1995</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c401t-8ee3a89746f430eea240079a4de1abc25fc7faa81ec5805182972570b848fe793</citedby><cites>FETCH-LOGICAL-c401t-8ee3a89746f430eea240079a4de1abc25fc7faa81ec5805182972570b848fe793</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.tandfonline.com/doi/pdf/10.3109/10428199509054769$$EPDF$$P50$$Ginformahealthcare$$H</linktopdf><linktohtml>$$Uhttps://www.tandfonline.com/doi/full/10.3109/10428199509054769$$EHTML$$P50$$Ginformahealthcare$$H</linktohtml><link.rule.ids>314,780,784,4022,27922,27923,27924,59646,59752,60435,60541,61220,61255,61401,61436</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8750639$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lipton, Jeffrey H.</creatorcontrib><creatorcontrib>McGowan, Hugh D.</creatorcontrib><creatorcontrib>Payne, David G.</creatorcontrib><title>Ocular Masquerade Syndrome in Lymphoid Blast Crisis of Chronic Myeloid Leukemia</title><title>Leukemia & lymphoma</title><addtitle>Leuk Lymphoma</addtitle><description>A 56-year-old woman presented with CML in lymphoid blast crisis. Complete remission with no suggestion of CML was achieved with chemotherapy. Twenty-six months later, an isolated ocular anterior chamber relapse of acute leukemia presenting as uveitis (ocular masquerade syndrome) was diagnosed and treated with radiotherapy. Ten months later, a second ocular relapse in the same location was diagnosed and treated with radiotherapy. Two months later, a systemic relapse into second chronic phase was diagnosed and is currently being treated with alpha interferon. Only one previous case of leukemic hypopyon in CML has been reported. This is also the first case of isolated ocular blast crisis relapse in CML to be described.</description><subject>Blast Crisis</subject><subject>Chronic myeloid leukemia</subject><subject>Cobalt Radioisotopes - therapeutic use</subject><subject>Eye Neoplasms - pathology</subject><subject>Eye Neoplasms - radiotherapy</subject><subject>Eye Neoplasms - secondary</subject><subject>Eye Neoplasms - therapy</subject><subject>Female</subject><subject>Humans</subject><subject>hypopyon</subject><subject>Interferon-alpha - therapeutic use</subject><subject>Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy</subject><subject>Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology</subject><subject>Leukemia, Myelogenous, Chronic, BCR-ABL Positive - therapy</subject><subject>masquerade syndrome</subject><subject>Middle Aged</subject><subject>ocular leukemia</subject><subject>Recurrence</subject><subject>Syndrome</subject><subject>Uveitis - etiology</subject><issn>1042-8194</issn><issn>1029-2403</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1995</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1r3DAQhkVpSNMkP6CHgk69OR3Z8kqivTRL0wY27CHJ2czKI1apbG0lm-J_Hy-7FEpJTjPwfvDyMPZBwFUlwHwWIEstjKnBQC3VwrxhZwJKU5QSqrf7X5bFbJDv2PucnwCgNovylJ1qVcOiMmdsvbZjwMTvMP8eKWFL_H7q2xQ74r7nq6nbbaNv-XXAPPBl8tlnHh1fblPsveV3E4W9vqLxF3UeL9iJw5Dp8njP2ePN94flz2K1_nG7_LYqrAQxFJqoQm2UXDhZARHOg0EZlC0J3NiydlY5RC3I1hpqoUujylrBRkvtSJnqnH069O5SnIfnoel8thQC9hTH3CilNWgpZqM4GG2KOSdyzS75DtPUCGj2EJv_IM6Zj8fycdNR-zdxpDbrXw-6711MHf6JKbTNgFOIySXsrc_76pfrv_wT3xKGYWsxUfMUx9TP3F4Z9wyW4pFT</recordid><startdate>1995</startdate><enddate>1995</enddate><creator>Lipton, Jeffrey H.</creator><creator>McGowan, Hugh D.</creator><creator>Payne, David G.</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1995</creationdate><title>Ocular Masquerade Syndrome in Lymphoid Blast Crisis of Chronic Myeloid Leukemia</title><author>Lipton, Jeffrey H. ; McGowan, Hugh D. ; Payne, David G.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c401t-8ee3a89746f430eea240079a4de1abc25fc7faa81ec5805182972570b848fe793</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1995</creationdate><topic>Blast Crisis</topic><topic>Chronic myeloid leukemia</topic><topic>Cobalt Radioisotopes - therapeutic use</topic><topic>Eye Neoplasms - pathology</topic><topic>Eye Neoplasms - radiotherapy</topic><topic>Eye Neoplasms - secondary</topic><topic>Eye Neoplasms - therapy</topic><topic>Female</topic><topic>Humans</topic><topic>hypopyon</topic><topic>Interferon-alpha - therapeutic use</topic><topic>Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy</topic><topic>Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology</topic><topic>Leukemia, Myelogenous, Chronic, BCR-ABL Positive - therapy</topic><topic>masquerade syndrome</topic><topic>Middle Aged</topic><topic>ocular leukemia</topic><topic>Recurrence</topic><topic>Syndrome</topic><topic>Uveitis - etiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lipton, Jeffrey H.</creatorcontrib><creatorcontrib>McGowan, Hugh D.</creatorcontrib><creatorcontrib>Payne, David G.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Leukemia & lymphoma</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lipton, Jeffrey H.</au><au>McGowan, Hugh D.</au><au>Payne, David G.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Ocular Masquerade Syndrome in Lymphoid Blast Crisis of Chronic Myeloid Leukemia</atitle><jtitle>Leukemia & lymphoma</jtitle><addtitle>Leuk Lymphoma</addtitle><date>1995</date><risdate>1995</risdate><volume>20</volume><issue>1-2</issue><spage>161</spage><epage>163</epage><pages>161-163</pages><issn>1042-8194</issn><eissn>1029-2403</eissn><abstract>A 56-year-old woman presented with CML in lymphoid blast crisis. Complete remission with no suggestion of CML was achieved with chemotherapy. Twenty-six months later, an isolated ocular anterior chamber relapse of acute leukemia presenting as uveitis (ocular masquerade syndrome) was diagnosed and treated with radiotherapy. Ten months later, a second ocular relapse in the same location was diagnosed and treated with radiotherapy. Two months later, a systemic relapse into second chronic phase was diagnosed and is currently being treated with alpha interferon. Only one previous case of leukemic hypopyon in CML has been reported. This is also the first case of isolated ocular blast crisis relapse in CML to be described.</abstract><cop>United States</cop><pub>Informa UK Ltd</pub><pmid>8750639</pmid><doi>10.3109/10428199509054769</doi><tpages>3</tpages></addata></record> |
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source | MEDLINE; Taylor & Francis Medical Library - CRKN; Taylor & Francis Journals Complete |
subjects | Blast Crisis Chronic myeloid leukemia Cobalt Radioisotopes - therapeutic use Eye Neoplasms - pathology Eye Neoplasms - radiotherapy Eye Neoplasms - secondary Eye Neoplasms - therapy Female Humans hypopyon Interferon-alpha - therapeutic use Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology Leukemia, Myelogenous, Chronic, BCR-ABL Positive - therapy masquerade syndrome Middle Aged ocular leukemia Recurrence Syndrome Uveitis - etiology |
title | Ocular Masquerade Syndrome in Lymphoid Blast Crisis of Chronic Myeloid Leukemia |
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