Dietary fat and fiber differentially alter intracellular second messengers during tumor development in rat colon

The effect of fat, fiber and carcinogen on colonic epithelial intracellular second messengers 1,2-diacyl-sn-glycerol (DAG), ceramide, and the steady-state level of phospholipase C (PLC-gamma1) was determined in 160 male Sprague-Dawley rats (10 rats per group). The study was a 2 x 2 x 2 x 2 factorial...

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Veröffentlicht in:Carcinogenesis (New York) 1996-06, Vol.17 (6), p.1227
Hauptverfasser: Jiang, Y H, Lupton, J R, Chang, W C, Jolly, C A, Aukema, H M, Chapkin, R S
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Sprache:eng
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