The loin-pain/haematuria syndrome
Nine patients with the loin-pain/haematuria syndrome are described. The previously reported clinical features of severe recurrent loin pain and tenderness in young women, the relationship of symptoms to use of oral contraceptives, and the demonstration of intrarenal vascular abnormalities by angiogr...
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| Veröffentlicht in: | The Lancet (British edition) 1979-04, Vol.1 (8122), p.897 |
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| creator | Burden, R P Dathan, J R Etherington, M D Guyer, P B MacIver, A G |
| description | Nine patients with the loin-pain/haematuria syndrome are described. The previously reported clinical features of severe recurrent loin pain and tenderness in young women, the relationship of symptoms to use of oral contraceptives, and the demonstration of intrarenal vascular abnormalities by angiography are confirmed. Histology revealed minor non-specific abnormalities, and electron microscopy showed fibrin in the afferent arteriole and in glomerular capillaries of one patient only. No diagnostic changes were found on renography. In all patients except one the heparin-thrombin clotting-time was abnormal, suggesting increased platelet activity or release and providing further evidence of a vascular disorder. |
| format | Article |
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The previously reported clinical features of severe recurrent loin pain and tenderness in young women, the relationship of symptoms to use of oral contraceptives, and the demonstration of intrarenal vascular abnormalities by angiography are confirmed. Histology revealed minor non-specific abnormalities, and electron microscopy showed fibrin in the afferent arteriole and in glomerular capillaries of one patient only. No diagnostic changes were found on renography. In all patients except one the heparin-thrombin clotting-time was abnormal, suggesting increased platelet activity or release and providing further evidence of a vascular disorder.</description><identifier>ISSN: 0140-6736</identifier><identifier>PMID: 86667</identifier><language>eng</language><publisher>England</publisher><subject>Adult ; Back Pain - diagnosis ; Colic - diagnosis ; Colic - etiology ; Diagnosis, Differential ; Estradiol Congeners - adverse effects ; Female ; Hematuria - diagnosis ; Hematuria - etiology ; Humans ; Kidney - blood supply ; Kidney Diseases - diagnosis ; Kidney Diseases - etiology ; Recurrence ; Syndrome ; Thrombosis - chemically induced ; Thrombosis - complications ; Thrombosis - diagnosis</subject><ispartof>The Lancet (British edition), 1979-04, Vol.1 (8122), p.897</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/86667$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Burden, R P</creatorcontrib><creatorcontrib>Dathan, J R</creatorcontrib><creatorcontrib>Etherington, M D</creatorcontrib><creatorcontrib>Guyer, P B</creatorcontrib><creatorcontrib>MacIver, A G</creatorcontrib><title>The loin-pain/haematuria syndrome</title><title>The Lancet (British edition)</title><addtitle>Lancet</addtitle><description>Nine patients with the loin-pain/haematuria syndrome are described. The previously reported clinical features of severe recurrent loin pain and tenderness in young women, the relationship of symptoms to use of oral contraceptives, and the demonstration of intrarenal vascular abnormalities by angiography are confirmed. Histology revealed minor non-specific abnormalities, and electron microscopy showed fibrin in the afferent arteriole and in glomerular capillaries of one patient only. No diagnostic changes were found on renography. In all patients except one the heparin-thrombin clotting-time was abnormal, suggesting increased platelet activity or release and providing further evidence of a vascular disorder.</description><subject>Adult</subject><subject>Back Pain - diagnosis</subject><subject>Colic - diagnosis</subject><subject>Colic - etiology</subject><subject>Diagnosis, Differential</subject><subject>Estradiol Congeners - adverse effects</subject><subject>Female</subject><subject>Hematuria - diagnosis</subject><subject>Hematuria - etiology</subject><subject>Humans</subject><subject>Kidney - blood supply</subject><subject>Kidney Diseases - diagnosis</subject><subject>Kidney Diseases - etiology</subject><subject>Recurrence</subject><subject>Syndrome</subject><subject>Thrombosis - chemically induced</subject><subject>Thrombosis - complications</subject><subject>Thrombosis - diagnosis</subject><issn>0140-6736</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1979</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNotjjsKwkAUALdQ_J_ARg-wuJu3P0sJ_kCwSS9vsy8YMTEkpsjtDWo1xcAwAzYRUgluLJgxmzbNQwihjNAjNnTGGDth6-ROq-crL3mFebm5IxX4buscV01XhvpV0JwNM3w2tPhzxpLDPolP_HI9nuPdhVdaWg4onN4GkpSmQRttIweOCFwG4BSh9F66IK1H15s0ZMrrSOis9xFoUDBjy1-2an1B4VbVeYF1d_t-wgfJKzbm</recordid><startdate>19790428</startdate><enddate>19790428</enddate><creator>Burden, R P</creator><creator>Dathan, J R</creator><creator>Etherington, M D</creator><creator>Guyer, P B</creator><creator>MacIver, A G</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope></search><sort><creationdate>19790428</creationdate><title>The loin-pain/haematuria syndrome</title><author>Burden, R P ; Dathan, J R ; Etherington, M D ; Guyer, P B ; MacIver, A G</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p517-3a0859de1eccd56572838ee38f3384ea1bb18d17ba8283cdf4b5205f8f3235343</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1979</creationdate><topic>Adult</topic><topic>Back Pain - diagnosis</topic><topic>Colic - diagnosis</topic><topic>Colic - etiology</topic><topic>Diagnosis, Differential</topic><topic>Estradiol Congeners - adverse effects</topic><topic>Female</topic><topic>Hematuria - diagnosis</topic><topic>Hematuria - etiology</topic><topic>Humans</topic><topic>Kidney - blood supply</topic><topic>Kidney Diseases - diagnosis</topic><topic>Kidney Diseases - etiology</topic><topic>Recurrence</topic><topic>Syndrome</topic><topic>Thrombosis - chemically induced</topic><topic>Thrombosis - complications</topic><topic>Thrombosis - diagnosis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Burden, R P</creatorcontrib><creatorcontrib>Dathan, J R</creatorcontrib><creatorcontrib>Etherington, M D</creatorcontrib><creatorcontrib>Guyer, P B</creatorcontrib><creatorcontrib>MacIver, A G</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><jtitle>The Lancet (British edition)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Burden, R P</au><au>Dathan, J R</au><au>Etherington, M D</au><au>Guyer, P B</au><au>MacIver, A G</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The loin-pain/haematuria syndrome</atitle><jtitle>The Lancet (British edition)</jtitle><addtitle>Lancet</addtitle><date>1979-04-28</date><risdate>1979</risdate><volume>1</volume><issue>8122</issue><spage>897</spage><pages>897-</pages><issn>0140-6736</issn><abstract>Nine patients with the loin-pain/haematuria syndrome are described. The previously reported clinical features of severe recurrent loin pain and tenderness in young women, the relationship of symptoms to use of oral contraceptives, and the demonstration of intrarenal vascular abnormalities by angiography are confirmed. Histology revealed minor non-specific abnormalities, and electron microscopy showed fibrin in the afferent arteriole and in glomerular capillaries of one patient only. No diagnostic changes were found on renography. In all patients except one the heparin-thrombin clotting-time was abnormal, suggesting increased platelet activity or release and providing further evidence of a vascular disorder.</abstract><cop>England</cop><pmid>86667</pmid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0140-6736 |
| ispartof | The Lancet (British edition), 1979-04, Vol.1 (8122), p.897 |
| issn | 0140-6736 |
| language | eng |
| recordid | cdi_pubmed_primary_86667 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Adult Back Pain - diagnosis Colic - diagnosis Colic - etiology Diagnosis, Differential Estradiol Congeners - adverse effects Female Hematuria - diagnosis Hematuria - etiology Humans Kidney - blood supply Kidney Diseases - diagnosis Kidney Diseases - etiology Recurrence Syndrome Thrombosis - chemically induced Thrombosis - complications Thrombosis - diagnosis |
| title | The loin-pain/haematuria syndrome |
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