The role of iron in cancer

Numerous laboratory and clinical investigations over the past few decades have observed that one of the dangers of iron is its ability to favour neoplastic cell growth. The metal is carcinogenic due to its catalytic effect on the formation of hydroxyl radicals, suppression of the activity of host de...

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Veröffentlicht in:	European journal of cancer prevention 1996-02, Vol.5 (1), p.19-36
1. Verfasser:	Weinberg, E D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Carcinogenesis, carcinogens and anticarcinogens Carcinogens - adverse effects Carrier Proteins - analysis Cell Division - drug effects Ferritins - biosynthesis Foods and miscellaneous Humans Hydroxyl Radical - metabolism Immunity, Cellular - drug effects Iron - adverse effects Iron - antagonists & inhibitors Iron - metabolism Iron - physiology Iron-Binding Proteins Macrophages - metabolism Medical sciences Neoplasms - etiology Neoplasms - pathology Neoplasms - prevention & control Neoplasms, Experimental - etiology Neoplasms, Experimental - pathology Neoplasms, Experimental - prevention & control Nitric Oxide - biosynthesis Receptors, Transferrin - analysis REVIEW Transferrin-Binding Proteins Tumors
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