Novel polypeptides induced by the insecticide lindane (gamma-hexachlorocyclohexane) are required for its biodegradation by a Sphingomonas paucimobilis strain
When exposed to the potent insecticide gamma-hexachlorocyclohexane or lindane, a Sphingomonas paucimobilis strain rapidly synthesised 7 novel polypeptides and concomitantly gained the ability to degrade lindane. Synthesis of these proteins was switched-off subsequent to the disappearance of lindane...
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| Veröffentlicht in: | Biochemical and biophysical research communications 1996-04, Vol.221 (3), p.755 |
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| container_title | Biochemical and biophysical research communications |
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| creator | Adhya, T.K. (Bhabha Atomic Research Centre, Trombay, Bombay, India.) Apte, S.K Raghu, K Sethunathan, N Murthy, N.B.K |
| description | When exposed to the potent insecticide gamma-hexachlorocyclohexane or lindane, a Sphingomonas paucimobilis strain rapidly synthesised 7 novel polypeptides and concomitantly gained the ability to degrade lindane. Synthesis of these proteins was switched-off subsequent to the disappearance of lindane from the medium. Treatments which induced the synthesis of identical proteins also conferred on cells the ability to degrade lindane. In contrast, cells blocked in protein synthesis could not be induced to degrade lindane. The close correspondence observed between expression of lindane-induced proteins and gamma-hexachlorocyclohexane catabolism strongly implicates these novel proteins in lindane biodegradation |
| doi_str_mv | 10.1006/bbrc.1996.0669 |
| format | Article |
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Treatments which induced the synthesis of identical proteins also conferred on cells the ability to degrade lindane. In contrast, cells blocked in protein synthesis could not be induced to degrade lindane. The close correspondence observed between expression of lindane-induced proteins and gamma-hexachlorocyclohexane catabolism strongly implicates these novel proteins in lindane biodegradation</abstract><cop>United States</cop><pmid>8630034</pmid><doi>10.1006/bbrc.1996.0669</doi></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0006-291X |
| ispartof | Biochemical and biophysical research communications, 1996-04, Vol.221 (3), p.755 |
| issn | 0006-291X 1090-2104 |
| language | eng |
| recordid | cdi_pubmed_primary_8630034 |
| source | Elsevier ScienceDirect Journals Complete - AutoHoldings; MEDLINE |
| subjects | ANTIMETABOLITE ANTIMETABOLITOS BACTERIA BIODEGRADACION BIODEGRADATION Biodegradation, Environmental FLORA DEL SUELO FLORE DU SOL HCH Insecticides - metabolism Insecticides - pharmacology LINDANE Lindane - metabolism Lindane - pharmacology LINDANO PEPTIDE Peptide Biosynthesis PEPTIDOS Pseudomonas - metabolism SINTESIS DE PROTEINAS SOL POLLUE SUELO CONTAMINADO SYNTHESE PROTEIQUE |
| title | Novel polypeptides induced by the insecticide lindane (gamma-hexachlorocyclohexane) are required for its biodegradation by a Sphingomonas paucimobilis strain |
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