Apoptotic and anti-proliferative effects of fumonisin B1 in human keratinocytes, fibroblasts, esophageal epithelial cells and hepatoma cells

Fumonisin B1 is associated with various animal and human carcinomas and toxicoses, including leukoencelphalomalacia, hepatocarcinoma, pulmonary edema and esophageal carcinoma. We have examined the cellular effects of fumonisin B1 in vitro using cellular model systems relevant to potential human targ...

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Veröffentlicht in:	Carcinogenesis (New York) 1996-02, Vol.17 (2), p.239-249
Hauptverfasser:	Tolleson, William H., Melchior, William B., Morris, Suzanne M., McGarrity, Lynda J., Domon, Olen E., Muskhelishvili, Levan, James, S.Jill, Howard, Paul C.
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 Cells - drug effects Animals Apoptosis - drug effects Biological and medical sciences Carcinogenesis, carcinogens and anticarcinogens Carcinogens, Environmental - pharmacology Carcinoma, Hepatocellular - pathology Cell Cycle - drug effects Cell Division - drug effects Cell Survival - drug effects DNA - biosynthesis DNA - drug effects Epithelial Cells Epithelium - drug effects Esophagus - cytology Esophagus - drug effects Foods and miscellaneous Fumonisins Humans Keratinocytes - cytology Keratinocytes - drug effects Keratinocytes - ultrastructure Liver Neoplasms - pathology Medical sciences Mice Microscopy, Electron Mycotoxins - pharmacology Tumor Cells, Cultured - drug effects Tumor Cells, Cultured - pathology Tumors
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