Acute Digitoxin Intoxication Treated by Intracardiac Pacemaker: Experience in Sixty-Eight Patients
Out of 124 patients who had taken massive doses of digitoxin in attempted suicide, emergency endocardial pacing was performed in the 68 with the worst prognosis. The mortality (13%) in the 124 patients compared favorably with the mortality (20%) in a previous series of 70 similar patients none of wh...
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| Veröffentlicht in: | Clinical toxicology 1977, Vol.10 (4), p.443-456 |
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| creator | BISMUTH, CHANTAL MOTTE, GILBERT CONSO, FRANÇOISE CHAUVIN, MICHEL GAULTIER, MICHEL |
| description | Out of 124 patients who had taken massive doses of digitoxin in attempted suicide, emergency endocardial pacing was performed in the 68 with the worst prognosis. The mortality (13%) in the 124 patients compared favorably with the mortality (20%) in a previous series of 70 similar patients none of whom were paced. Sixteen (23%) of the 68 paced patients died. The causes of death were: asystole (two); cardiogenic shock (two); septicemia (one); and ventricular fibrillation (eleven). Ventricular fibrillation occurred during introduction of the pacing catheter in two patients, as a result of electrode displacement in these patients, because of premature withdrawal of the catheter in one patient, and for no detectable reason, during normally proceeding pacing, in five patients. Endocardial pacing has a place in the emergency treatment of massive digitoxin poisoning. Its chief hazards are mechanical, and one of the commonest is electrode displacement. |
| doi_str_mv | 10.3109/15563657709046282 |
| format | Article |
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The mortality (13%) in the 124 patients compared favorably with the mortality (20%) in a previous series of 70 similar patients none of whom were paced. Sixteen (23%) of the 68 paced patients died. The causes of death were: asystole (two); cardiogenic shock (two); septicemia (one); and ventricular fibrillation (eleven). Ventricular fibrillation occurred during introduction of the pacing catheter in two patients, as a result of electrode displacement in these patients, because of premature withdrawal of the catheter in one patient, and for no detectable reason, during normally proceeding pacing, in five patients. Endocardial pacing has a place in the emergency treatment of massive digitoxin poisoning. Its chief hazards are mechanical, and one of the commonest is electrode displacement.</description><identifier>ISSN: 1556-3650</identifier><identifier>ISSN: 0009-9309</identifier><identifier>EISSN: 1556-9519</identifier><identifier>DOI: 10.3109/15563657709046282</identifier><identifier>PMID: 862379</identifier><language>eng</language><publisher>United States: Informa UK Ltd</publisher><subject>Adolescent ; Adult ; Age Factors ; Aged ; Arrhythmias, Cardiac - chemically induced ; Catheterization ; Digitoxin - poisoning ; Electrocardiography ; Female ; Humans ; Male ; Middle Aged ; Pacemaker, Artificial ; Potassium - blood ; Time Factors</subject><ispartof>Clinical toxicology, 1977, Vol.10 (4), p.443-456</ispartof><rights>1977 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 1977</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c315t-e7f12b73c552684866db929a7a48caa303652c557b4eae02f748c8b8c76e52673</citedby><cites>FETCH-LOGICAL-c315t-e7f12b73c552684866db929a7a48caa303652c557b4eae02f748c8b8c76e52673</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.tandfonline.com/doi/pdf/10.3109/15563657709046282$$EPDF$$P50$$Ginformaworld$$H</linktopdf><linktohtml>$$Uhttps://www.tandfonline.com/doi/full/10.3109/15563657709046282$$EHTML$$P50$$Ginformaworld$$H</linktohtml><link.rule.ids>314,777,781,4010,27904,27905,27906,59626,60415,61200,61235,61381,61416</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/862379$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>BISMUTH, CHANTAL</creatorcontrib><creatorcontrib>MOTTE, GILBERT</creatorcontrib><creatorcontrib>CONSO, FRANÇOISE</creatorcontrib><creatorcontrib>CHAUVIN, MICHEL</creatorcontrib><creatorcontrib>GAULTIER, MICHEL</creatorcontrib><title>Acute Digitoxin Intoxication Treated by Intracardiac Pacemaker: Experience in Sixty-Eight Patients</title><title>Clinical toxicology</title><addtitle>Clin Toxicol</addtitle><description>Out of 124 patients who had taken massive doses of digitoxin in attempted suicide, emergency endocardial pacing was performed in the 68 with the worst prognosis. The mortality (13%) in the 124 patients compared favorably with the mortality (20%) in a previous series of 70 similar patients none of whom were paced. Sixteen (23%) of the 68 paced patients died. The causes of death were: asystole (two); cardiogenic shock (two); septicemia (one); and ventricular fibrillation (eleven). Ventricular fibrillation occurred during introduction of the pacing catheter in two patients, as a result of electrode displacement in these patients, because of premature withdrawal of the catheter in one patient, and for no detectable reason, during normally proceeding pacing, in five patients. Endocardial pacing has a place in the emergency treatment of massive digitoxin poisoning. Its chief hazards are mechanical, and one of the commonest is electrode displacement.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Age Factors</subject><subject>Aged</subject><subject>Arrhythmias, Cardiac - chemically induced</subject><subject>Catheterization</subject><subject>Digitoxin - poisoning</subject><subject>Electrocardiography</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Pacemaker, Artificial</subject><subject>Potassium - blood</subject><subject>Time Factors</subject><issn>1556-3650</issn><issn>0009-9309</issn><issn>1556-9519</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1977</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kN1Kw0AQhRfxr1YfQPAiLxDdnySbqDelVi0UFKzXYbKZtFubpGy22Ly9G1IEEb2a5Zz5DrOHkEtGrwWjyQ0Lw0hEoZQ0oUHEY35ABp3mJyFLDvdvt0BPyVnTrCgVcZCwE3IcR1zIZECykdpa9B70Qtt6pytvWnVTgdV15c0NgsXcy9pON6DA5BqU9woKS_hAc-tNdhs0GiuFnqPf9M62_kQvltYtWafb5pwcFbBu8GI_h-T9cTIfP_uzl6fpeDTzlWCh9VEWjGdSqDDkURzEUZRnCU9AQhArAEHdN7gzZRYgIOWFdHqcxUpG6AgphoT1ucrUTWOwSDdGl2DalNG0ayv91ZZjrnpms81KzL-Jvh5n3_e2roralPBZm3WeWmjXtSkMVEo3XfLf6Xc_8CXC2i5diZiu6q2pXBv_3PYF1TSKqg</recordid><startdate>1977</startdate><enddate>1977</enddate><creator>BISMUTH, CHANTAL</creator><creator>MOTTE, GILBERT</creator><creator>CONSO, FRANÇOISE</creator><creator>CHAUVIN, MICHEL</creator><creator>GAULTIER, MICHEL</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>1977</creationdate><title>Acute Digitoxin Intoxication Treated by Intracardiac Pacemaker: Experience in Sixty-Eight Patients</title><author>BISMUTH, CHANTAL ; MOTTE, GILBERT ; CONSO, FRANÇOISE ; CHAUVIN, MICHEL ; GAULTIER, MICHEL</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c315t-e7f12b73c552684866db929a7a48caa303652c557b4eae02f748c8b8c76e52673</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1977</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Age Factors</topic><topic>Aged</topic><topic>Arrhythmias, Cardiac - chemically induced</topic><topic>Catheterization</topic><topic>Digitoxin - poisoning</topic><topic>Electrocardiography</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Pacemaker, Artificial</topic><topic>Potassium - blood</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>BISMUTH, CHANTAL</creatorcontrib><creatorcontrib>MOTTE, GILBERT</creatorcontrib><creatorcontrib>CONSO, FRANÇOISE</creatorcontrib><creatorcontrib>CHAUVIN, MICHEL</creatorcontrib><creatorcontrib>GAULTIER, MICHEL</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Clinical toxicology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>BISMUTH, CHANTAL</au><au>MOTTE, GILBERT</au><au>CONSO, FRANÇOISE</au><au>CHAUVIN, MICHEL</au><au>GAULTIER, MICHEL</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Acute Digitoxin Intoxication Treated by Intracardiac Pacemaker: Experience in Sixty-Eight Patients</atitle><jtitle>Clinical toxicology</jtitle><addtitle>Clin Toxicol</addtitle><date>1977</date><risdate>1977</risdate><volume>10</volume><issue>4</issue><spage>443</spage><epage>456</epage><pages>443-456</pages><issn>1556-3650</issn><issn>0009-9309</issn><eissn>1556-9519</eissn><abstract>Out of 124 patients who had taken massive doses of digitoxin in attempted suicide, emergency endocardial pacing was performed in the 68 with the worst prognosis. The mortality (13%) in the 124 patients compared favorably with the mortality (20%) in a previous series of 70 similar patients none of whom were paced. Sixteen (23%) of the 68 paced patients died. The causes of death were: asystole (two); cardiogenic shock (two); septicemia (one); and ventricular fibrillation (eleven). Ventricular fibrillation occurred during introduction of the pacing catheter in two patients, as a result of electrode displacement in these patients, because of premature withdrawal of the catheter in one patient, and for no detectable reason, during normally proceeding pacing, in five patients. Endocardial pacing has a place in the emergency treatment of massive digitoxin poisoning. Its chief hazards are mechanical, and one of the commonest is electrode displacement.</abstract><cop>United States</cop><pub>Informa UK Ltd</pub><pmid>862379</pmid><doi>10.3109/15563657709046282</doi><tpages>14</tpages></addata></record> |
| fulltext | fulltext |
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| ispartof | Clinical toxicology, 1977, Vol.10 (4), p.443-456 |
| issn | 1556-3650 0009-9309 1556-9519 |
| language | eng |
| recordid | cdi_pubmed_primary_862379 |
| source | MEDLINE; Taylor & Francis Medical Library - CRKN; Taylor & Francis Journals Complete |
| subjects | Adolescent Adult Age Factors Aged Arrhythmias, Cardiac - chemically induced Catheterization Digitoxin - poisoning Electrocardiography Female Humans Male Middle Aged Pacemaker, Artificial Potassium - blood Time Factors |
| title | Acute Digitoxin Intoxication Treated by Intracardiac Pacemaker: Experience in Sixty-Eight Patients |
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