Influence of paternal (252) Cf neutron exposure on abnormal sperm, embryonal lethality, and liver tumorigenesis in the F(1) offspring of mice

Experiments were conducted to determine whether neutron-induced genetic damage in parental germline cells can lead to development of cancer in the offspring. Seven-week-old C3H male mice were irradiated with (252) Cf neutrons at a dose of 0, 50, 100, or 200 cGy. Two weeks or three months after irrad...

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Veröffentlicht in:	Japanese journal of cancer research (Gann) 1996-01, Vol.87 (1), p.51
Hauptverfasser:	Watanabe, H, Takahashi, T, Lee, J Y, Ohtaki, M, Roy, G, Ando, Y, Yamada, K, Gotoh, T, Kurisu, K, Fujimoto, N, Satow, Y, Ito, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Birth Rate Californium - adverse effects Dose-Response Relationship, Radiation Fathers Female Fetal Death - etiology Liver Neoplasms, Experimental - etiology Liver Neoplasms, Experimental - genetics Male Mice Mice, Inbred C3H Mice, Inbred C57BL Neoplasms, Radiation-Induced - etiology Neoplasms, Radiation-Induced - genetics Neutrons - adverse effects Organ Size - radiation effects Pregnancy Spermatozoa - radiation effects Testis - radiation effects Time Factors Whole-Body Irradiation
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