AGN 191976: a novel thromboxane A2-mimetic with ocular hypotensive properties

The possible subdivision of thromboxane A2-sensitive (TP) receptors is currently a controversial subject. We report herein on a novel thromboxane A2 mimetic, AGN 191976, which has almost identical pharmacological activity to the well-characterized prostaglandin H2/thromboxane A2 (PGH2/TxA2) mimetic...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of ocular pharmacology and therapeutics 1995, Vol.11 (3), p.203-212
Hauptverfasser:	KRAUSS, A. H.-P, WOODWARD, D. F, CHEN, J, GIBSON, L. L, LAI, R. K, PROTZMAN, C. E, SHAN, T, WILLIAMS, L. S, GAC, T. S, BURK, R. M
Format:	Artikel
Sprache:	eng
Schlagworte:	15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid Aged Animals Antihypertensive Agents - pharmacology Biological and medical sciences Blood Platelets - drug effects Bridged Bicyclo Compounds, Heterocyclic - pharmacology Capillary Permeability - drug effects Conjunctiva - blood supply Dogs Eye Female Guinea Pigs Humans Hydrazines - pharmacology Intraocular Pressure - drug effects Macaca fascicularis Male Medical sciences Muscle, Smooth - drug effects Ocular Hypertension - chemically induced Ophthalmic Solutions Pharmacology. Drug treatments Platelet Aggregation - drug effects Prostaglandin Endoperoxides, Synthetic - pharmacology Pupil - drug effects Receptors, Thromboxane - antagonists & inhibitors Receptors, Thromboxane - metabolism Thromboxane A2 - analogs & derivatives Thromboxane A2 - metabolism Thromboxane A2 - pharmacology Tonometry, Ocular Vasoconstrictor Agents - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!